Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 2/20 | 0.50 |
| ▸ | F12 | P00748 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | NOS3 | P29474 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30327401 | 1.00 | CYP2A6 (0.55) | CYP2A6PLAUF12NCF1NOS3 | |
| Iodide SCHEMBL3633184 | 0.98 | CYP2A6 (0.53) | CYP2A6PLAUF12NCF1NOS3 | |
| Bromide SCHEMBL5146590 | 0.98 | CYP2A6 (0.53) | CYP2A6PLAUF12NCF1NOS3 | |
| Aniline SCHEMBL27488059 | 0.89 | PLAU (0.50) | CYP2A6PLAUF12NCF1NOS3 | |
| SCHEMBL30179063 | 0.84 | CYP2A6 (0.52) | CYP2A6PLAUF12NCF1NOS3 | |
| SCHEMBL4066216 | 0.84 | CYP2A6 (0.52) | CYP2A6PLAUF12NCF1NOS3 | |
| SCHEMBL12128484 | 0.82 | CYP2A6 (0.50) | CYP2A6PLAUF12NCF1NOS3 | |
| SCHEMBL1445844 | 0.82 | CYP2A6 (0.46) | CYP2A6PLAUF12NCF1NOS3 | |
| SCHEMBL4067893 | 0.81 | CYP2A6 (0.48) | CYP2A6PLAUF12NCF1NOS3 | |
| SCHEMBL31125170 | 0.81 | CYP2A6 (0.48) | CYP2A6PLAUF12NCF1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796800-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2017-10-24 | — | — | US | claimed |
| US-20160108153-A1 | PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORPORATION (JP) | 2016-04-21 | — | — | US | claimed |
| US-9249244-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2016-02-02 | — | — | US | claimed |
| CN-103435456-B | Preparation method for 9-fluorenone | BAOSHUN TECHNOLOGY CO LTD | 2015-06-10 | — | — | CN | claimed |
| EP-1761517-B1 | NOVEL IMIDAZOLES AND TRIAZOLES, THE PRODUCTION THEREOF, AND THE USE OF THE SAME AS MEDICAMENTS | BOEHRINGER INGELHEIM INT (DE) | 2014-09-24 | — | — | EP | claimed |
| CN-103435456-A | Preparation method for 9-fluorenone | BAOSHUN TECHNOLOGY CO LTD | 2013-12-11 | — | — | CN | claimed |
| EP-2619233-A1 | PROCESS FOR PRODUCING POLYDIENES | Bridgestone Corporation (JP) | 2013-07-31 | — | — | EP | claimed |
| WO-2012040026-A1 | PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORPORATION (JP) | 2012-03-29 | — | — | WO | claimed |
| US-7906539-B2 | e.g. 1-(but-2-ynyl)-2-(3-amino-piperidin-1-yl)-5-(naphth-1-ylmethylaminocarbonyl)-1H-imidazole; dipeptidylpeptidase-IV inhibitor; antidiabetic, anticarcinogenic, antiinflammatory agent; autoimmune, neurodegenerative diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-15 | — | — | US | claimed |
| US-7470716-B2 | Imidazoles and triazoles, their preparation, and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-12-30 | — | — | US | claimed |
| US-20080312243-A1 | IMIDAZOLES AND TRIAZOLES, THEIR PREPARATION, AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | ECKHARDT MATTHIAS | 2008-12-18 | — | — | US | claimed |
| US-7393847-B2 | Imidazopyridazinediones, their preparation and their use as pharmaceutical compositions | BOEHRINGER INGLEHEIM INTERNATIONAL GMBH (DE) | 2008-07-01 | — | — | US | claimed |
| US-20060004074-A1 | New imidazoles and triazoles, their preparation, and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-01-05 | — | — | US | claimed |
| US-20050203095-A1 | Imidazopyridazinediones, their preparation and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-09-15 | — | — | US | claimed |
| CN-116283759-B | Preparation method of 2-monofluoromethylquinoline and derivatives thereof | 济南大学 | 2025-02-28 | — | — | CN | disclosed |
| EP-4328230-A2 | AMINO ACID COMPOUNDS AND METHODS OF USE | Pliant Therapeutics, Inc. (US) | 2024-02-28 | — | — | EP | disclosed |
| US-11787796-B2 | Plasma Kallikrein inhibitors and uses thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-17 | — | — | US | disclosed |
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| US-4255283-A | METAL PHOSPHATE CATALYST | THE STANDARD OIL COMPANY (US) | 1981-03-10 | — | — | US | disclosed |
| US-4246421-A | METAL PHOSPHATE CATALYST | THE STANDARD OIL COMPANY (US) | 1981-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787796-B2 | Plasma Kallikrein inhibitors and uses thereof | KLKB1, KLK1, KLK5 | CYP2A6 2270/4885PLAU 15/4885F12 61/4885 |
| US-20050203095-A1 | Imidazopyridazinediones, their preparation and their use as pharmaceutical compositions | DPP4, DPP3, DPP7 | CYP2A6 367/4885PLAU 401/4885F12 666/4885 |
| US-20060004074-A1 | New imidazoles and triazoles, their preparation, and their use as pharmaceutical compositions | DPP4, DPP3, DPP7 | CYP2A6 753/4885PLAU 894/4885F12 325/4885 |
| US-20080312243-A1 | IMIDAZOLES AND TRIAZOLES, THEIR PREPARATION, AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | DPP4, DPP3, DPP7 | CYP2A6 642/4885PLAU 769/4885F12 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.