Ethylene Glycol

Ethylene Glycol

SCHEMBL8732912

C1CCC1.CCCOCCC.OCCO

nearest known ligand 0.48

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
THRB P10828 1/20 0.42
HTT P42858 1/20 0.42
MAPT P10636 1/20 0.42
MAPK1 P28482 1/20 0.42
ALDH1A1 P00352 3/20 0.41
HSD17B10 Q99714 2/20 0.40
TDP1 Q9NUW8 1/20 0.33
USP2 O75604 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
EPHX2 P34913 1/20 0.31
SPHK2 Q9NRA0 1/20 0.31
LMNA P02545 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL55660 0.91 TSHR (0.55) TSHRMEN1KMT2ATHRBHTT
Ethylene Glycol SCHEMBL6728641 0.88 TSHR (0.52) TSHRMEN1KMT2ATHRBHTT
Ethylene Glycol SCHEMBL28138591 0.88 MEN1 (0.53) TSHRMEN1KMT2ATHRBHTT
Ethylene Glycol SCHEMBL10834271 0.85 TSHR (0.50) TSHRMEN1KMT2ATHRBHTT
Ethylene Glycol SCHEMBL386937 0.85 TSHR (0.50) TSHRMEN1KMT2ATHRBHTT
Ethylene Glycol SCHEMBL18890187 0.85 TSHR (0.50) TSHRMEN1KMT2ATHRBHTT
Ethylene Glycol SCHEMBL7799597 0.85 TSHR (0.50) TSHRMEN1KMT2ATHRBHTT
Ethylene Glycol SCHEMBL989836 0.85 TSHR (0.50) TSHRMEN1KMT2ATHRBHTT
Ethylene Glycol SCHEMBL987769 0.85 TSHR (0.50) TSHRMEN1KMT2ATHRBHTT
Ethylene Glycol SCHEMBL27466313 0.85 TSHR (0.65) TSHRMEN1KMT2ATHRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0686681-B1 Alpha-cyanoacrylate adhesive composition TAOKA CHEMICAL CO LTD (JP) 1998-08-05 EP disclosed
EP-0686681-A1 Alpha-cyanoacrylate adhesive composition TAOKA CHEMICAL COMPANY, LIMITED (JP) 1995-12-13 EP disclosed
EP-0063037-B1 ADHESIVE COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-09-25 EP disclosed
US-4377490-A CYANOACRYLATE, ETHERS, ALCOHOLS, ACIDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-03-22 US disclosed
EP-0063037-A2 Adhesive composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-10-20 EP disclosed