Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8729241 | 1.00 | CETP (0.40) | CETPS1PR1S1PR4S1PR3S1PR2 | |
| SCHEMBL8732993 | 1.00 | CETP (0.40) | CETPS1PR1S1PR4S1PR3S1PR2 | |
| SCHEMBL8728138 | 0.97 | CETP (0.41) | CETPS1PR1S1PR4S1PR3S1PR2 | |
| SCHEMBL8727543 | 0.96 | CETP (0.43) | CETPLPAR1LPAR3 | |
| SCHEMBL8733266 | 0.96 | CETP (0.43) | CETPLPAR1LPAR3 | |
| SCHEMBL8733385 | 0.96 | CETP (0.43) | CETPLPAR1LPAR3 | |
| SCHEMBL8733051 | 0.96 | CETP (0.43) | CETPLPAR1LPAR3 | |
| SCHEMBL8726823 | 0.96 | CETP (0.43) | CETPLPAR1LPAR3 | |
| SCHEMBL8730268 | 0.96 | CETP (0.43) | CETPLPAR1LPAR3 | |
| SCHEMBL8732298 | 0.96 | CETP (0.43) | CETPLPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0701561-B1 | DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 | MENARINI LAB (ES) | 1998-08-19 | — | — | EP | disclosed |