Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 3/20 | 0.35 |
| ▸ | NPY1R | P25929 | 2/20 | 0.35 |
| ▸ | NPY2R | P49146 | 2/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL162756 | 0.92 | FOLH1 (0.38) | FOLH1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL17769024 | 0.92 | FOLH1 (0.38) | FOLH1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL93472 | 0.92 | FOLH1 (0.38) | FOLH1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL93473 | 0.92 | FOLH1 (0.38) | FOLH1NPY4RNPY1RNPY2RNPY5R | |
| Hydrochloric Acid SCHEMBL1578565 | 0.91 | FOLH1 (0.37) | FOLH1NPY4RNPY1RNPY2RNPY5R | |
| Hydrochloric Acid SCHEMBL974818 | 0.91 | FOLH1 (0.37) | FOLH1NPY4RNPY1RNPY2RNPY5R | |
| Hydrochloric Acid SCHEMBL7367067 | 0.91 | FOLH1 (0.37) | FOLH1NPY4RNPY1RNPY2RNPY5R | |
| Arginine SCHEMBL3421641 | 0.91 | GSR (0.51) | SIRT6SIRT1FOLH1GNAI3GNAO1 | |
| Gamma-Aminobutyric Acid SCHEMBL8958845 | 0.90 | FOLH1 (0.43) | FOLH1NPY4RNPY1RNPY2RNPY5R | |
| Acetic Acid SCHEMBL160844 | 0.89 | FOLH1 (0.39) | FOLH1NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797442-A4 | TREATMENT OF OPTIC NEURITIS | MASSACHUSETTS EYE & EAR INFIRM (US) | 1998-04-15 | — | — | EP | disclosed |
| EP-0797442-A1 | TREATMENT OF OPTIC NEURITIS | MASSACHUSETTS EYE & EAR INFIRMARY (US) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996000073-A1 | TREATMENT OF OPTIC NEURITIS | MASSACHUSETTS EYE AND EAR INFIRMARY (US) | 1996-01-04 | — | — | WO | disclosed |