Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734422 | 0.91 | ASAH2 (0.43) | S1PR2S1PR1S1PR3CETP | |
| SCHEMBL8728148 | 0.86 | AR (0.36) | — | |
| SCHEMBL8733007 | 0.83 | ASAH2 (0.36) | S1PR2S1PR1S1PR3 | |
| SCHEMBL8729245 | 0.83 | ASAH2 (0.36) | S1PR2S1PR1S1PR3 | |
| SCHEMBL8733000 | 0.83 | ASAH2 (0.36) | S1PR2S1PR1S1PR3 | |
| SCHEMBL8734261 | 0.82 | ASAH2 (0.43) | — | |
| SCHEMBL8733089 | 0.82 | ASAH2 (0.43) | — | |
| SCHEMBL8729196 | 0.82 | ASAH2 (0.43) | — | |
| SCHEMBL8733270 | 0.80 | ASAH2 (0.38) | CETP | |
| SCHEMBL8731343 | 0.80 | ASAH2 (0.38) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0701561-B1 | DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 | MENARINI LAB (ES) | 1998-08-19 | — | — | EP | disclosed |
| EP-0830145-A1 | FORMULATIONS FOR LIPOPHILIC COMPOUNDS | Sugen, Inc. (US) | 1998-03-25 | — | — | EP | disclosed |
| EP-0804191-A1 | TREATMENT OF PLATELET DERIVED GROWTH FACTOR RELATED DISORDERS SUCH AS CANCERS USING INHIBITORS OF PLATELET DERIVED GROWTH RECEPTOR | Sugen, Inc. (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996033745-A1 | FORMULATIONS FOR LIPOPHILIC COMPOUNDS | SUGEN, INC. (US) | 1996-10-31 | — | — | WO | disclosed |
| WO-1996033179-A1 | THIOAMIDES DERIVATES AND THEIR USE AS INHIBITORS OF HYPER-PROLIFERATIVE CELL GROWTH | SUGEN, INC. (US) | 1996-10-24 | — | — | WO | disclosed |
| EP-0701561-A1 | DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 | LABORATORIOS MENARINI S.A. (ES) | 1996-03-20 | — | — | EP | disclosed |
| WO-1995019169-A2 | TREATMENT OF PLATELET DERIVED GROWTH FACTOR RELATED DISORDERS SUCH AS CANCER USING INHIBITORS OF PLATELET DERIVED GROWTH FACTOR RECEPTOR | SUGEN, INC. (US) | 1995-07-20 | — | — | WO | disclosed |
| WO-1994028004-A1 | DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 | LABORATORIOS MENARINI S.A. (ES) | 1994-12-08 | — | — | WO | disclosed |