Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 5/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 1.00 |
| ▸ | HTR1A | P08908 | 1/20 | 0.98 |
| ▸ | HTR2A | P28223 | 1/20 | 0.98 |
| ▸ | HTR2C | P28335 | 1/20 | 0.98 |
| ▸ | HRH1 | P35367 | 1/20 | 0.98 |
| ▸ | HTR2B | P41595 | 1/20 | 0.98 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.98 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.98 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6700496 | 1.00 | TACR1 (1.00) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| SCHEMBL156646 | 1.00 | TACR1 (1.00) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| SCHEMBL29754193 | 1.00 | TACR1 (1.00) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| SCHEMBL119933 | 1.00 | TACR1 (1.00) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| SCHEMBL29870266 | 1.00 | TACR1 (1.00) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL8731569 | 0.99 | TACR1 (1.00) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL29407476 | 0.99 | TACR1 (1.00) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL8731566 | 0.99 | TACR1 (1.00) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL4913461 | 0.99 | TACR1 (1.00) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| SCHEMBL4912732 | 0.97 | TACR1 (0.94) | TACR1CYP2D6KCNH2HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663349-A | Preparation of substituted piperidenes | PFIZER INC (US) | 1997-09-02 | — | — | US | claimed |
| EP-0619806-A1 | PREPARATION OF SUBSTITUTED PIPERIDINES. | PFIZER (US) | 1994-10-19 | — | — | EP | claimed |
| WO-1993011110-A1 | PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER INC. (US) | 1993-06-10 | — | — | WO | claimed |
| EP-0690835-B1 | FORMYLATION PROCESS FOR AROMATIC ALDEHYDES | PFIZER (US) | 1998-08-19 | — | — | EP | disclosed |
| US-5663349-A | Preparation of substituted piperidenes | PFIZER INC (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0619806-B1 | PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER (US) | 1996-01-03 | — | — | EP | disclosed |
| US-5364943-A | Preparation of substituted piperidines | PFIZER INC. (US) | 1994-11-15 | — | — | US | disclosed |
| EP-0619806-A1 | PREPARATION OF SUBSTITUTED PIPERIDINES. | PFIZER (US) | 1994-10-19 | — | — | EP | disclosed |
| WO-1993011110-A1 | PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER INC. (US) | 1993-06-10 | — | — | WO | disclosed |