Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.53 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1975997 | 0.98 | FGFR1 (0.54) | FGFR1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL434799 | 0.76 | NPC1 (0.58) | FGFR1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL20698180 | 0.74 | FGFR1 (0.54) | FGFR1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL21900387 | 0.74 | FGFR1 (0.54) | FGFR1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4967369 | 0.74 | FGFR1 (0.54) | FGFR1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL15241833 | 0.74 | FGFR1 (0.54) | FGFR1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4580483 | 0.74 | FGFR1 (0.58) | FGFR1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL19911321 | 0.73 | FGFR1 (0.53) | FGFR1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11055266 | 0.73 | FGFR1 (0.53) | FGFR1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL19911318 | 0.72 | NPC1 (0.61) | FGFR1GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804668-A | PREPARED FROM AMIDINES, ZINC MERCAPTO COMPOUNDS, ELASTOMERS; IMPROVED STORAGE STABILITY, AGING RESISTANCE | BAYER AG (DE) | 1998-09-08 | — | — | US | disclosed |