SCHEMBL8733761

SCHEMBL8733761

C[C](C)c1cccc2c1C(C1=CC=CC1)c1ccccc1-2

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9068334 0.84
Hydrochloric Acid SCHEMBL8776363 0.80
SCHEMBL8857757 0.80 POLB (0.31) POLB
SCHEMBL7625234 0.80 SLC6A2 (0.31) SLC6A2SLC6A4SLC6A3
SCHEMBL6437443 0.80 SLC6A2 (0.31) SLC6A2SLC6A4SLC6A3
SCHEMBL8853881 0.80 SLC6A4 (0.41) POLBSLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL5688623 0.79
SCHEMBL8895357 0.79 SLC6A2 (0.30) SLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL8776347 0.79
Hydrochloric Acid SCHEMBL4120454 0.79 SLC6A2 (0.31) SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0595390-B1 Catalyst and process for (co)polymerizing alpha-olefins ENICHEM SPA (IT) 1998-07-15 EP claimed
EP-0595390-A1 Catalyst and process for (co)polymerizing alpha-olefins ENICHEM S.p.A. (IT) 1994-05-04 EP claimed
EP-0595390-B1 Catalyst and process for (co)polymerizing alpha-olefins ENICHEM SPA (IT) 1998-07-15 EP disclosed
US-5529966-A BIS/CYCLOPENTADIENEYL BIS/AMINE DERIVATIVE OF GROUP 4 ELEMENT AS POLYMERIZATION CATALYST AND ALUMINOXANE AS COCATALYST ENICHEM S.P.A. (IT) 1996-06-25 US disclosed
EP-0595390-A1 Catalyst and process for (co)polymerizing alpha-olefins ENICHEM S.p.A. (IT) 1994-05-04 EP disclosed