Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.80 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8732779 | 0.90 | CYSLTR1 (0.79) | CYSLTR1ADAMTS4GPBAR1 | |
| SCHEMBL8734127 | 0.89 | CYSLTR1 (1.00) | CYSLTR1ADAMTS4GPBAR1 | |
| SCHEMBL8735662 | 0.85 | CYSLTR1 (0.67) | CYSLTR1GPBAR1 | |
| SCHEMBL8733699 | 0.85 | CYSLTR1 (0.70) | CYSLTR1ADAMTS4 | |
| SCHEMBL8734143 | 0.83 | CYSLTR1 (0.86) | CYSLTR1ADAMTS4 | |
| SCHEMBL8736033 | 0.82 | CYSLTR1 (0.85) | CYSLTR1ADAMTS4 | |
| SCHEMBL8736040 | 0.80 | CYSLTR1 (0.60) | CYSLTR1 | |
| SCHEMBL8734190 | 0.80 | CYSLTR1 (0.81) | CYSLTR1ADAMTS4 | |
| SCHEMBL8736469 | 0.80 | CYSLTR1 (0.72) | CYSLTR1GPBAR1 | |
| SCHEMBL8736452 | 0.78 | CYSLTR1 (0.74) | CYSLTR1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874826-A1 | NAPHTHALENE QUINOLINES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1998-11-04 | — | — | EP | claimed |
| WO-1997024331-A1 | NAPHTHALENE QUINOLINES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-07-10 | — | — | WO | claimed |
| EP-0874826-A1 | NAPHTHALENE QUINOLINES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997024331-A1 | NAPHTHALENE QUINOLINES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-07-10 | — | — | WO | disclosed |