Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944495 | 0.86 | GRM2 (0.44) | GRM2GRM3GRM4CYP1A2ALOX15 | |
| SCHEMBL151899 | 0.86 | GRM2 (0.44) | GRM2GRM3GRM4CYP1A2ALOX15 | |
| SCHEMBL353161 | 0.86 | GRM2 (0.44) | GRM2GRM3GRM4CYP1A2ALOX15 | |
| SCHEMBL353162 | 0.86 | GRM2 (0.44) | GRM2GRM3GRM4CYP1A2ALOX15 | |
| SCHEMBL9134965 | 0.86 | GRM2 (0.44) | GRM2GRM3GRM4CYP1A2ALOX15 | |
| SCHEMBL6944486 | 0.86 | GRM2 (0.44) | GRM2GRM3GRM4CYP1A2ALOX15 | |
| SCHEMBL8639606 | 0.80 | — | — | |
| SCHEMBL8640668 | 0.80 | — | — | |
| SCHEMBL8640662 | 0.80 | — | — | |
| SCHEMBL7745103 | 0.75 | PEPD (0.39) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656335-B1 | Process for the production of hydroxy compounds by hydrogenation of oxygenates | EASTMAN CHEM CO (US) | 1998-07-29 | — | — | EP | claimed |