SCHEMBL8734112

SCHEMBL8734112

CCC(OC(=O)C=CC(=O)OC(CC)[Si]1(O[Si](C)(C)C)CCC(C)(C)O[Si]1(C)O[Si](C)(C)C)[Si]1(O[Si](C)(C)C)CCC(C)(C)O[Si]1(C)O[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10771024 0.96 HCAR2 (0.32)
SCHEMBL9576371 0.96
SCHEMBL8735971 0.96 HCAR2 (0.32)
SCHEMBL9576310 0.94 HCAR2 (0.31)
SCHEMBL9576312 0.93
SCHEMBL9576395 0.93
SCHEMBL9576289 0.90 HCAR2 (0.39)
SCHEMBL8736690 0.89
SCHEMBL8734555 0.89
SCHEMBL9576287 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0722959-B1 Highly oxygen-permeable heat-resistant material MENICON CO LTD (JP) 1998-04-08 EP disclosed
EP-0600269-B1 Soft ocular lens material MENICON CO LTD (JP) 1998-02-04 EP disclosed
EP-0722959-A2 Highly oxygen-permeable heat-resistant material Menicon Co., Ltd. (JP) 1996-07-24 EP disclosed
EP-0219884-B1 HARD CONTACT LENS MATERIAL Tomei Sangyo Kabushiki Kaisha (JP) 1993-09-29 EP disclosed
US-4868260-A OXYGEN PERMEABILITY TOMEI SANGYO KABUSHIKI KAISHA (JP) 1989-09-19 US disclosed
EP-0219884-A2 Hard contact lens material Tomei Sangyo Kabushiki Kaisha (JP) 1987-04-29 EP disclosed