SCHEMBL8734331

SCHEMBL8734331

C=CC(O)c1ccc(OP(=O)(Oc2ccccc2)Oc2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.43
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
ACP3 P15309 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ANPEP P15144 1/20 0.38
LAP3 P28838 1/20 0.38
NPSR1 Q6W5P4 3/20 0.38
POLB P06746 1/20 0.38
SRD5A2 P31213 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
LMNA P02545 1/20 0.36
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8618583 0.81 SRD5A2 (0.50) TSHRHRH3SRD5A2
SCHEMBL30665501 0.78 SRD5A2 (0.50) SRCCYP3A4TSHRACP3NPSR1
SCHEMBL21840438 0.78 TSHR (0.48) SRCCYP3A4TSHRTDP1L3MBTL1
SCHEMBL131239 0.76 CYP3A4 (0.61) SRCCYP3A4TSHRTDP1L3MBTL1
SCHEMBL10015245 0.76 CYP3A4 (0.61) SRCCYP3A4TSHRTDP1L3MBTL1
SCHEMBL10015247 0.76 CYP3A4 (0.61) SRCCYP3A4TSHRTDP1L3MBTL1
Triphenyl Phosphate SCHEMBL8079334 0.75 TSHR (0.56) SRCCYP3A4TSHRTDP1L3MBTL1
Triphenyl Phosphate SCHEMBL27578973 0.75 SRC (0.56) SRCCYP3A4TSHRTDP1L3MBTL1
Triphenyl Phosphate SCHEMBL28322017 0.75 CYP3A4 (0.50) SRCCYP3A4TSHRTDP1L3MBTL1
SCHEMBL3893413 0.74 TSHR (0.43) SRCTSHRL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5817857-A (4-Hydroxy-alkylphenyl diphenyl phosphate flame rerardants AKZO NOBEL NV (NL) 1998-10-06 US disclosed