Sb-209670

Sb-209670

SCHEMBL8734573

CCCOc1ccc2c(c1)C(c1ccc(OC)cc1OCC(=O)O)C(C(=O)O)[C@H]2c1ccc2c(c1)OCO2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EDNRA P25101 20/20 1.00
EDNRB P24530 15/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sb-209670 SCHEMBL29550762 1.00 EDNRA (1.00) EDNRAEDNRB
Sb-209670 SCHEMBL4197810 1.00 EDNRA (1.00) EDNRAEDNRB
Sb-209670 SCHEMBL1028671 1.00 EDNRA (1.00) EDNRAEDNRB
Sb-209670 SCHEMBL6953911 0.99 EDNRA (0.98) EDNRAEDNRB
Sb-209670 SCHEMBL7532946 0.99 EDNRA (0.98) EDNRAEDNRB
Sb-209670 SCHEMBL6953904 0.99 EDNRA (0.98) EDNRAEDNRB
Sb-209670 SCHEMBL7664400 0.99 EDNRA (0.98) EDNRAEDNRB
SCHEMBL8204582 0.97 EDNRA (0.94) EDNRAEDNRB
SCHEMBL8203979 0.95 EDNRA (0.93) EDNRAEDNRB
SCHEMBL13038489 0.95 EDNRA (0.93) EDNRAEDNRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5811416-A ADMINISTERING TO TREAT DISORDERS SUCH AS DYSMENORRHEA, PRETERM LABOR, PREECLAMPSIA, OR FETAL GROWTH RETARDATION; ALSO HORMONE REPLACEMENT THERAPY, HYPERTENSION BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM (US) 1998-09-22 US disclosed