Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.65 |
| ▸ | CTSS | P25774 | 4/20 | 0.61 |
| ▸ | PPARG | P37231 | 2/20 | 0.59 |
| ▸ | KLK5 | Q9Y337 | 4/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | KLK7 | P49862 | 2/20 | 0.51 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338282 | 1.00 | PPARA (0.65) | PPARACTSSPPARGKLK5CA1 | |
| SCHEMBL25467761 | 0.91 | PPARA (0.63) | PPARACTSSPPARGKLK5CA1 | |
| SCHEMBL25467796 | 0.90 | PPARA (0.62) | PPARACTSSPPARGKLK5KLK7 | |
| SCHEMBL20296945 | 0.88 | PPARA (0.63) | PPARACTSSPPARGKLK5KLK7 | |
| SCHEMBL506387 | 0.86 | PPARA (0.67) | PPARACTSSPPARGKLK5CA1 | |
| SCHEMBL23390363 | 0.86 | PPARA (0.67) | PPARACTSSPPARGKLK5CA1 | |
| SCHEMBL506388 | 0.86 | PPARA (0.67) | PPARACTSSPPARGKLK5CA1 | |
| SCHEMBL25467795 | 0.86 | PPARA (0.57) | PPARACTSSPPARGKLK5CA1 | |
| SCHEMBL8288878 | 0.85 | PPARA (0.66) | PPARACTSSPPARGKLK5CA1 | |
| SCHEMBL13537922 | 0.85 | PPARA (0.60) | PPARACTSSPPARGKLK5KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716973-A | ADMINISTERING DIFLUORO STATONE ANALOGS | MERRELL PHARMACEUTICALS INC. (US) | 1998-02-10 | — | — | US | disclosed |
| US-5559140-A | VIRICIDES | MERRELL PHARMACEUTICALS INC. (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0565631-B1 | ANTI-VIRAL COMPOUNDS | MERRELL PHARMA INC (US) | 1996-09-18 | — | — | EP | disclosed |
| EP-0565631-A1 | ANTI-VIRAL COMPOUNDS. | MERRELL DOW PHARMA (US) | 1993-10-20 | — | — | EP | disclosed |
| WO-1992012123-A1 | ANTI-VIRAL COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-23 | — | — | WO | disclosed |