Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 15/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8731707 | 0.89 | TBXA2R (0.80) | TBXA2RKMT2AHDAC8CA12CA1 | |
| SCHEMBL8733286 | 0.85 | TBXA2R (0.79) | TBXA2RKMT2AHDAC8 | |
| SCHEMBL8758408 | 0.83 | TBXA2R (0.72) | TBXA2RKMT2AHDAC8 | |
| SCHEMBL8758383 | 0.82 | TBXA2R (0.70) | TBXA2RKMT2AHDAC8 | |
| SCHEMBL8757797 | 0.82 | TBXA2R (0.70) | TBXA2RKMT2AHDAC8 | |
| SCHEMBL8757825 | 0.81 | TBXA2R (0.82) | TBXA2RHDAC8CA12CA1CA2 | |
| SCHEMBL5673556 | 0.80 | TBXA2R (0.85) | TBXA2R | |
| SCHEMBL8757016 | 0.79 | TBXA2R (0.82) | TBXA2RHDAC8CA12CA1CA2 | |
| SCHEMBL8757821 | 0.78 | TBXA2R (0.83) | TBXA2RHDAC8CA12CA1CA2 | |
| SCHEMBL8757830 | 0.78 | TBXA2R (0.67) | TBXA2RKMT2AHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750524-A | ADMINISTERING AN SULFAMIDE SUBSTITUTED INDAN DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |