Propionic Acid

Propionic Acid

SCHEMBL8734813

CCC(=O)O.CCSC(C)(SCC)C(=O)O

nearest known ligand 0.48

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.48
TSHR P16473 3/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
HIF1A Q16665 1/20 0.37
ALDH1A1 P00352 2/20 0.33
HMGCR P04035 1/20 0.33
CHRM1 P11229 1/20 0.33
TBXA2R P21731 1/20 0.33
ADRA1A P35348 1/20 0.33
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
THRB P10828 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10924273 0.93 TSHR (0.38) FFAR3TSHRCYP2D6CYP2C19HIF1A
Propionic Acid SCHEMBL11771473 0.80 FFAR3 (0.42) FFAR3TSHRCYP2D6CYP2C19HIF1A
Propionic Acid SCHEMBL11803120 0.79 FFAR3 (0.40) FFAR3TSHRALDH1A1MEN1THRB
Propionic Acid SCHEMBL2535266 0.79 FFAR3 (0.40) FFAR3TSHRCYP2D6CYP2C19HIF1A
Propionic Acid SCHEMBL3162345 0.78 FFAR3 (0.50) FFAR3TSHRCYP2D6CYP2C19HIF1A
Propionic Acid SCHEMBL11771893 0.77 FFAR3 (0.39) FFAR3TSHRCYP2D6CYP2C19HIF1A
Propionic Acid SCHEMBL11799570 0.76 HSD17B10 (0.48) TSHRALDH1A1MEN1THRBKMT2A
Propionic Acid SCHEMBL724024 0.76 HSD17B10 (0.48) TSHRALDH1A1MEN1THRBKMT2A
Propionic Acid SCHEMBL21413182 0.76 HSD17B10 (0.48) TSHRALDH1A1MEN1THRBKMT2A
Propionic Acid SCHEMBL21409823 0.76 HSD17B10 (0.48) TSHRALDH1A1MEN1THRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102655858-B ABT-263 capsule ABBVIE (US) 2015-11-25 CN disclosed
EP-0623555-B1 Stabilized, halogen-containing resin composition, and composite metal oxide and process for the production thereof KAISUI KAGAKU KENKYUJO KK (JP) 1998-07-15 EP disclosed
US-5466740-A Stabilized, halogen-containing resin composition, and composite metal oxide and process for the production thereof KABUSHIKI KAISHA KAISUI KAGAKU KENKYOJO (JP) 1995-11-14 US disclosed
EP-0623555-A1 Stabilized, halogen-containing resin composition, and composite metal oxide and process for the production thereof KABUSHIKI KAISHA KAISUI KAGAKU KENKYUJO (JP) 1994-11-09 EP disclosed
EP-0076630-B1 COLOR STABLE CHELATED TITANATE COMPOSITIONS DOW CORNING CORPORATION (US) 1986-01-22 EP disclosed
US-4482498-A RTV SILICONE RESIN CURING CATALYSTS DOW CORNING CORPORATION (US) 1984-11-13 US disclosed
US-4391937-A ROOM TEMPERATURE-VULCANIZABLE, MOISTURE-CURABLE SILICONE RUBBERS; STABILIZERS DOW CORNING CORPORATION (US) 1983-07-05 US disclosed
EP-0076630-A2 Color stable chelated titanate compositions DOW CORNING CORPORATION (US) 1983-04-13 EP disclosed