Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 2/20 | 0.55 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.55 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.55 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.47 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25226579 | 0.94 | GRIN2D (0.50) | GRIN2DGRIN3BTHRBGRIN1GRIN2A | |
| SCHEMBL7449088 | 0.88 | ANPEP (0.51) | GRIN2DGRIN3BTHRBGRIN1GRIN2A | |
| SCHEMBL13992928 | 0.86 | ANPEP (0.50) | GRIN2DGRIN3BTHRBGRIN1GRIN2A | |
| SCHEMBL10653943 | 0.85 | ANPEP (0.48) | GRIN2DGRIN3BTHRBGRIN1GRIN2A | |
| SCHEMBL5669350 | 0.85 | ANPEP (0.48) | GRIN2DGRIN3BTHRBGRIN1GRIN2A | |
| SCHEMBL9709649 | 0.81 | HRH3 (0.48) | GRIN2DGRIN3BTHRBGRIN1GRIN2A | |
| SCHEMBL14444591 | 0.80 | CXCR4 (0.47) | GRIN2DGRIN3BTHRBGRIN1GRIN2A | |
| Phosphoric Acid SCHEMBL31591102 | 0.78 | S1PR1 (0.50) | ANPEPERAP2CXCR4SIGMAR1MEN1 | |
| SCHEMBL6667225 | 0.76 | CHRM2 (0.46) | LMNAANPEPERAP2CXCR4SIGMAR1 | |
| SCHEMBL18985137 | 0.76 | CXCR4 (0.43) | GRIN2DGRIN3BTHRBGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603301-B1 | PHARMACEUTICAL PREPARATION CONTAINING AN URICOSURIC AND AN EXCITATORY AMINO ACID ANTAGONIST | WARNER LAMBERT CO (US) | 1998-01-14 | — | — | EP | claimed |