SCHEMBL873587

SCHEMBL873587

COc1cccc2ccc(C)nc12

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 1/20 0.65
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
METAP2 P50579 1/20 0.55
CCR1 P32246 1/20 0.54
RAB9A P51151 1/20 0.54
CCR5 P51681 1/20 0.54
PDE10A Q9Y233 1/20 0.51
KDM4E B2RXH2 2/20 0.51
BDKRB2 P30411 1/20 0.51
LMNA P02545 1/20 0.51
HTT P42858 1/20 0.51
TSHR P16473 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
ALDH1A1 P00352 1/20 0.50
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL28875612 0.84 PDE10A (0.53) MCHR1MEN1KMT2ARAB9APDE10A
SCHEMBL20561242 0.82 MEN1 (0.54) MCHR1MEN1KMT2AMETAP2CCR1
SCHEMBL2092748 0.82 MEN1 (0.54) MCHR1MEN1KMT2AMETAP2CCR1
SCHEMBL19603062 0.82 MCHR1 (0.67) MCHR1KMT2ARAB9APDE10AKDM4E
SCHEMBL24375928 0.81 MEN1 (0.53) MCHR1MEN1KMT2AMETAP2CCR1
SCHEMBL27576259 0.81 MEN1 (0.55) MCHR1MEN1KMT2AMETAP2CCR1
SCHEMBL10029548 0.81 MEN1 (0.65) MCHR1MEN1KMT2AMETAP2CCR1
SCHEMBL28886096 0.81 CCR1 (0.56) MCHR1MEN1KMT2AMETAP2CCR1
SCHEMBL15648746 0.80 MCHR1 (0.65) MCHR1MEN1KMT2ARAB9APDE10A
SCHEMBL873240 0.80 MCHR1 (0.70) MCHR1PDE10AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112979619-A Method for catalyzing dehydrogenation coupling reaction of nitrogen heteroaromatic ring compound and cyclic ether by using Bronsted acid 青岛职业技术学院 2021-06-18 CN claimed
CN-110075900-A The mesoporous carbon-silica catalyst material and preparation method and application of supported palladium 上海师范大学 2019-08-02 CN claimed
EP-2265677-B1 CORROSION DETECTION PRODUCT AND METHOD BATTELLE MEMORIAL INSTITUTE (US) 2019-05-15 EP claimed
CN-104447539-B A kind of two grades, the synthetic method of three-level aromatic amides 湖南大学 2017-09-15 CN claimed
US-9321730-B2 Method of making and administering quinoline derivatives as anti-cancer agents THE HONG KONG POLYTECHNIC UNIVERSITY (HK) 2016-04-26 US claimed
CN-105418605-A Improved preparation method for nitrogenous tricyclic dopamine D3 acceptor ligand UNIV SOUTHEAST 2016-03-23 CN claimed
CN-104447540-A Synthetic method of primary aryl amide compounds UNIV HUNAN 2015-03-25 CN claimed
CN-104447539-A Method for synthesizing binary and ternary aryl amide compounds UNIV HUNAN 2015-03-25 CN claimed
CN-1150168-C Amphiphili 8-hydroxyquinoline complex, its preparing process and its application in electroluminescence 暨南大学 2004-05-19 CN claimed
CN-1282735-A Amphiphili 8-hydroxyquinoline complex, its preparing process and its application in electroluminescence UNIV JINAN (CN) 2001-02-07 CN claimed
CN-116283759-B Preparation method of 2-monofluoromethylquinoline and derivatives thereof 济南大学 2025-02-28 CN disclosed
US-20230322803-A1 SUBSTITUTED OXOISOINDOLINE COMPOUNDS FOR THE TREATMENT OF CANCER BRISTOL MYERS SQUIBB CO (US) 2023-10-12 US disclosed
EP-3269789-B1 LIGHT EMITTING MATERIAL AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2023-08-30 EP disclosed
US-11731994-B2 Organometallic compound, organic light-emitting device including the organometallic compound, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-08-22 US disclosed
US-20230233689-A1 Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins UNIV YALE (US) 2023-07-27 US disclosed
CN-1282735-A Amphiphili 8-hydroxyquinoline complex, its preparing process and its application in electroluminescence UNIV JINAN (CN) 2001-02-07 CN disclosed
EP-0952832-A1 QUINOLINE CARBOXAMIDES AS TNF INHIBITORS AND AS PDE-IV INHIBITORS Darwin Discovery Limited (GB) 1999-11-03 EP disclosed
US-5804588-A TREATING DISEASES THAT ARE MODULATED BY INHIBITION OF PHOSPHODIESTERASE IV OR TUMOUR NECROSIS FACTOR CHIROSCIENCE LIMITED (GB) 1998-09-08 US disclosed
WO-1997044036-A1 QUINOLINE CARBOXAMIDES AS TNF INHIBITORS AND AS PDE-IV INHIBITORS DARWIN DISCOVERY LIMITED (GB) 1997-11-27 WO disclosed
EP-0480276-A2 Carbonylaminostyrene derivatives as recording material BAYER AG (DE) 1992-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11731994-B2 Organometallic compound, organic light-emitting device including the organometallic compound, and diagnostic composition including the organometallic compound CYBA, CYC1, C1S MCHR1 2152/4885MEN1 44/4885KMT2A 2721/4885
US-20230322803-A1 SUBSTITUTED OXOISOINDOLINE COMPOUNDS FOR THE TREATMENT OF CANCER DDX21, HRAS, RPL17 MCHR1 4218/4885MEN1 717/4885KMT2A 1071/4885
US-20230233689-A1 Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins ASGR1, LDLR, FCGR2A MCHR1 976/4885MEN1 4131/4885KMT2A 3629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.