Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 3/20 | 0.70 |
| ▸ | LCK | P06239 | 1/20 | 0.70 |
| ▸ | FYN | P06241 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5837058 | 1.00 | FFAR3 (0.70) | FFAR3LCKFYNALDH1A1TDP1 | |
| Acetic Acid SCHEMBL9051977 | 1.00 | — | — | |
| Acetic Acid SCHEMBL4302337 | 0.95 | — | — | |
| Acetic Acid SCHEMBL3782093 | 0.95 | FFAR3 (0.64) | FFAR3LCKFYNALDH1A1TDP1 | |
| Acetic Acid SCHEMBL8334784 | 0.91 | FFAR3 (0.58) | FFAR3LCKFYNALDH1A1TDP1 | |
| Acetic Acid SCHEMBL8472368 | 0.88 | FFAR3 (0.54) | FFAR3LCKFYNALDH1A1TDP1 | |
| Acetic Acid SCHEMBL6419058 | 0.88 | FFAR3 (0.54) | FFAR3LCKFYNALDH1A1TDP1 | |
| Acetic Acid SCHEMBL6290880 | 0.86 | FFAR3 (0.64) | FFAR3LCKFYNALDH1A1TDP1 | |
| Acetic Acid SCHEMBL15090782 | 0.86 | FFAR3 (0.64) | FFAR3LCKFYNALDH1A1TDP1 | |
| Acetic Acid SCHEMBL15689725 | 0.86 | FFAR3 (0.64) | FFAR3LCKFYNALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4552634-A | Radiation hardened lift-off correction medium and process of manufacture | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1985-11-12 | — | — | US | claimed |
| CN-106999374-B | Perfume composition | 奇华顿股份有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-109070134-A | anti-fog coating | SDC 科技有限公司 | 2018-12-21 | — | — | CN | disclosed |
| EP-0516925-B1 | Wrinkled absorbent particles of high effective surface area having fast absorption rate | DOW CHEMICAL CO (US) | 1998-05-06 | — | — | EP | disclosed |
| WO-1993025393-A1 | ULTRAVIOLET PROTECTIVE COATINGS FOR HEAT SENSITIVE RECORD MATERIALS | DOI ALFRED (US) | 1993-12-23 | — | — | WO | disclosed |
| EP-0424219-A2 | Polycarbonate-polyol composition and polycarbonate (meth) acrylate compositions and urethane (meth) acrylate compositions prepared therefrom | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1991-04-24 | — | — | EP | disclosed |