Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 16/20 | 0.58 |
| ▸ | PIP5K1C | O60331 | 3/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.43 |
| ▸ | PIP5K1B | O14986 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | PIP5K1A | Q99755 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8737596 | 0.92 | NPY2R (0.63) | NPY2RKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8737473 | 0.91 | NPY2R (0.61) | NPY2RKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8737449 | 0.90 | NPY2R (0.60) | NPY2RKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL13873603 | 0.90 | NPY2R (0.57) | NPY2RPIP5K1CPIK3CAPIP5K1BMAPK8 | |
| SCHEMBL8737930 | 0.89 | NPY2R (0.63) | NPY2RPIP5K1CPIK3CAPIP5K1BMAPK8 | |
| SCHEMBL8737591 | 0.87 | NPY2R (0.59) | NPY2RKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL6115368 | 0.85 | NPY2R (0.68) | NPY2RKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL6116011 | 0.83 | NPY2R (0.70) | NPY2RKDM4EMEN1KMT2A | |
| SCHEMBL8737923 | 0.83 | NPY2R (0.55) | NPY2RMAPK8MAPK10MAPK14MEN1 | |
| SCHEMBL4128647 | 0.81 | NPY2R (0.84) | NPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129870-A1 | PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2012-05-24 | — | — | US | disclosed |
| WO-2009079597-A1 | PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129870-A1 | PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | NPY2R, NPY1R, NPY5R | NPY2R 1/4885PIP5K1C 1245/4885PIK3CA 2500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.