Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9224228 | 0.93 | MEN1 (0.38) | MAOBMAOACYP1A2MEN1KMT2A | |
| SCHEMBL9224226 | 0.93 | MEN1 (0.38) | MAOBMAOACYP1A2MEN1KMT2A | |
| SCHEMBL8110112 | 0.90 | MAOB (0.36) | MAOBMAOAHRH3FYNCYP2C9 | |
| SCHEMBL8110108 | 0.90 | MAOB (0.36) | MAOBMAOAHRH3FYNCYP2C9 | |
| SCHEMBL8904980 | 0.90 | MAOB (0.36) | MAOBMAOAHRH3FYNCYP2C9 | |
| SCHEMBL7918728 | 0.89 | TRPV1 (0.35) | CYP1A2HRH3FYN | |
| SCHEMBL7918738 | 0.89 | TRPV1 (0.35) | CYP1A2HRH3FYN | |
| SCHEMBL7918734 | 0.89 | TRPV1 (0.35) | CYP1A2HRH3FYN | |
| SCHEMBL6458044 | 0.84 | TLR4 (0.35) | MAOBMAOAFYN | |
| SCHEMBL6458041 | 0.84 | TLR4 (0.35) | MAOBMAOAFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846670-A1 | CYCLOHEXANE DERIVATIVES AND LIQUID-CRYSTAL COMPOSITIONS | CHISSO CORPORATION (JP) | 1998-06-10 | — | — | EP | disclosed |