Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 1.00 |
| ▸ | S1PR4 | O95977 | 2/20 | 1.00 |
| ▸ | S1PR3 | Q99500 | 2/20 | 1.00 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | S1PR2 | O95136 | 1/20 | 1.00 |
| ▸ | TSPO | P30536 | 1/20 | 1.00 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 1.00 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 1.00 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | GMNN | O75496 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | CETP | P11597 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29438139 | 1.00 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL17482409 | 1.00 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL12766764 | 1.00 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL6055753 | 1.00 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL2561998 | 1.00 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL3517452 | 1.00 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL3885 | 1.00 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL22910837 | 1.00 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL20798182 | 1.00 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL29963390 | 1.00 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170114125-A1 | METHODS OF TREATING DISEASE USING ANTIBODIES TO LYSOPHOSPHATIDIC ACID | APOLLO ENDOSURGERY INTERNATIONAL, LLC | 2017-04-27 | — | — | US | disclosed |
| US-20170114125-A1 | METHODS OF TREATING DISEASE USING ANTIBODIES TO LYSOPHOSPHATIDIC ACID | APOLLO ENDOSURGERY INTERNATIONAL, LLC | 2017-04-27 | — | — | US | disclosed |
| US-20170088634-A1 | TREATMENT OF NEUROTRAUMA USING ANTIBODIES TO LYSOPHOSPHATIDIC ACID | APOLLO ENDOSURGERY, INC. | 2017-03-30 | — | — | US | disclosed |
| US-20170088634-A1 | TREATMENT OF NEUROTRAUMA USING ANTIBODIES TO LYSOPHOSPHATIDIC ACID | APOLLO ENDOSURGERY, INC. | 2017-03-30 | — | — | US | disclosed |
| US-20160168270-A1 | PREVENTION AND TREATMENT OF PAIN USING ANTIBODIES TO LYSOPHOSPHATIDIC ACID | APOLLO ENDOSURGERY, INC. | 2016-06-16 | — | — | US | disclosed |
| US-20160152735-A1 | COMPOSITIONS AND METHODS FOR BINDING LYSOPHOSPHATIDIC ACID | APOLLO ENDOSURGERY, INC. | 2016-06-02 | — | — | US | disclosed |
| US-20160152735-A1 | COMPOSITIONS AND METHODS FOR BINDING LYSOPHOSPHATIDIC ACID | APOLLO ENDOSURGERY, INC. | 2016-06-02 | — | — | US | disclosed |
| US-20160146844-A1 | COMPOSITIONS AND METHODS FOR BINDING LYSOPHOSPHATIDIC ACID | APOLLO ENDOSURGERY, INC. | 2016-05-26 | — | — | US | disclosed |
| US-20160075775-A1 | TREATMENT OF TRAUMATIC BRAIN INJURY USING ANTIBODIES TO LYSOPHOSPHATIDIC ACID | APOLLO ENDOSURGERY, INC. | 2016-03-17 | — | — | US | disclosed |
| US-9274129-B2 | Methods and reagents for detecting bioactive lipids | LPATH, INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-20090074720-A1 | METHODS FOR DECREASING IMMUNE RESPONSE AND TREATING IMMUNE CONDITIONS | SABBADINI ROGER A | 2009-03-19 | — | — | US | disclosed |
| US-20080213274-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF FIBROTIC, INFLAMMATORY, AND NEOVASCULARIZATION CONDITIONS OF THE EYE | LPATH, INC. | 2008-09-04 | — | — | US | disclosed |
| US-20080213274-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF FIBROTIC, INFLAMMATORY, AND NEOVASCULARIZATION CONDITIONS OF THE EYE | LPATH, INC. | 2008-09-04 | — | — | US | disclosed |
| US-20080145360-A1 | Lysolipid specific immunoglobulin for use in diagnosis, prevention and treatment of blood and cell proliferative disorders | INNOVATUS LIFE SCIENCES LENDING FUND I, LP | 2008-06-19 | — | — | US | disclosed |
| US-20080145360-A1 | Lysolipid specific immunoglobulin for use in diagnosis, prevention and treatment of blood and cell proliferative disorders | INNOVATUS LIFE SCIENCES LENDING FUND I, LP | 2008-06-19 | — | — | US | disclosed |
| US-20080138334-A1 | Immune-Derived Moieties Reactive Against Bioactive Lipids, and Methods of Making and Using Same | SABBADINI ROGER A | 2008-06-12 | — | — | US | disclosed |
| US-20080090303-A1 | Methods and Reagents for Detecting Bioactive Lipids | APOLLO ENDOSURGERY, INC. | 2008-04-17 | — | — | US | disclosed |
| US-20070280933-A1 | Methods for decreasing immune response and treating immune conditions | APOLLO ENDOSURGERY, INC. | 2007-12-06 | — | — | US | disclosed |
| US-20070148168-A1 | Compositions and methods for the treatment and prevention of fibrotic, inflammatory and neovascularization conditions | LPATH, INC. | 2007-06-28 | — | — | US | disclosed |
| US-20070148168-A1 | Compositions and methods for the treatment and prevention of fibrotic, inflammatory and neovascularization conditions | LPATH, INC. | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075775-A1 | TREATMENT OF TRAUMATIC BRAIN INJURY USING ANTIBODIES TO LYSOPHOSPHATIDIC ACID | LPAR5, LPAR4, LPAR2 | S1PR1 70/4885S1PR4 59/4885S1PR3 87/4885 |
| US-20160168270-A1 | PREVENTION AND TREATMENT OF PAIN USING ANTIBODIES TO LYSOPHOSPHATIDIC ACID | LPAR5, LPAR6, LPAR2 | S1PR1 177/4885S1PR4 135/4885S1PR3 131/4885 |
| US-20070280933-A1 | Methods for decreasing immune response and treating immune conditions | LPAR1, LPAR2, S1PR1 | S1PR1 3/4885S1PR4 8/4885S1PR3 9/4885 |
| US-20170114125-A1 | METHODS OF TREATING DISEASE USING ANTIBODIES TO LYSOPHOSPHATIDIC ACID | LPAR5, LPAR2, LPAR6 | S1PR1 125/4885S1PR4 118/4885S1PR3 115/4885 |
| US-20080145360-A1 | Lysolipid specific immunoglobulin for use in diagnosis, prevention and treatment of blood and cell proliferative disorders | CD47, SGMS1, ALG1 | S1PR1 9/4885S1PR4 18/4885S1PR3 15/4885 |
| US-20170088634-A1 | TREATMENT OF NEUROTRAUMA USING ANTIBODIES TO LYSOPHOSPHATIDIC ACID | LPAR4, LPAR5, LPAR1 | S1PR1 72/4885S1PR4 58/4885S1PR3 97/4885 |
| US-20080213274-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF FIBROTIC, INFLAMMATORY, AND NEOVASCULARIZATION CONDITIONS OF THE EYE | S1PR1, S1PR5, S1PR3 | S1PR1 1/4885S1PR4 11/4885S1PR3 3/4885 |
| US-20080138334-A1 | Immune-Derived Moieties Reactive Against Bioactive Lipids, and Methods of Making and Using Same | CD47, ALG1, SGMS1 | S1PR1 12/4885S1PR4 20/4885S1PR3 17/4885 |
| US-20090074720-A1 | METHODS FOR DECREASING IMMUNE RESPONSE AND TREATING IMMUNE CONDITIONS | LPAR1, LPAR2, S1PR1 | S1PR1 3/4885S1PR4 8/4885S1PR3 9/4885 |
| US-20070148168-A1 | Compositions and methods for the treatment and prevention of fibrotic, inflammatory and neovascularization conditions | S1PR1, S1PR5, S1PR3 | S1PR1 1/4885S1PR4 8/4885S1PR3 3/4885 |
| US-20160152735-A1 | COMPOSITIONS AND METHODS FOR BINDING LYSOPHOSPHATIDIC ACID | LPAR2, LPAR3, LPAR5 | S1PR1 200/4885S1PR4 159/4885S1PR3 128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.