Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 16/20 | 0.71 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8738662 | 0.94 | EZH2 (0.76) | EZH2SMPD1ATML3MBTL1 | |
| SCHEMBL8738617 | 0.92 | EZH2 (0.65) | EZH2SMPD1 | |
| SCHEMBL8738629 | 0.88 | EZH2 (0.74) | EZH2ATML3MBTL1 | |
| SCHEMBL8738206 | 0.87 | EZH2 (0.73) | EZH2SMPD1ATML3MBTL1 | |
| SCHEMBL8738594 | 0.86 | EZH2 (0.77) | EZH2ATML3MBTL1 | |
| SCHEMBL8738653 | 0.85 | EZH2 (0.70) | EZH2SMPD1ATML3MBTL1 | |
| SCHEMBL8739659 | 0.85 | EZH2 (0.76) | EZH2ATML3MBTL1 | |
| SCHEMBL8738204 | 0.85 | EZH2 (0.69) | EZH2SMPD1ATML3MBTL1 | |
| SCHEMBL8738211 | 0.84 | EZH2 (0.68) | EZH2ATML3MBTL1 | |
| SCHEMBL8738576 | 0.84 | EZH2 (0.68) | EZH2ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068589-A2 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS (US) | 2012-05-24 | — | — | WO | disclosed |