SCHEMBL8738210

SCHEMBL8738210

CNc1ccc(Nc2ccc(Nc3ccc(C)cc3)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.64
GAA P10253 4/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
G6PD P11413 1/20 0.52
RAPGEF4 Q8WZA2 1/20 0.50
MAPT P10636 2/20 0.46
TSHR P16473 2/20 0.46
EGFR P00533 1/20 0.45
TDP1 Q9NUW8 4/20 0.45
ACHE P22303 1/20 0.44
APP P05067 2/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
LMNA P02545 1/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPK1 P28482 2/20 0.42
HAO1 Q9UJM8 1/20 0.42
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL471119 1.00 HPGD (0.64) HPGDGAAMEN1KMT2AL3MBTL1
SCHEMBL2620355 1.00 HPGD (0.64) HPGDGAAMEN1KMT2AL3MBTL1
SCHEMBL44533 0.91
SCHEMBL13573418 0.89 HPGD (0.52) HPGDGAAMEN1KMT2AL3MBTL1
Hydrochloric Acid SCHEMBL2866389 0.88 MAPT (0.50) HPGDMEN1KMT2ARAPGEF4MAPT
SCHEMBL108881 0.88 HPGD (0.78) HPGDGAAMEN1KMT2AL3MBTL1
SCHEMBL50079 0.88 HPGD (0.78) HPGDGAAMEN1KMT2AL3MBTL1
SCHEMBL7338618 0.88 TSHR (0.56) HPGDGAAL3MBTL1MAPTTSHR
SCHEMBL9516537 0.88 HPGD (0.78) HPGDGAAMEN1KMT2AL3MBTL1
SCHEMBL19248249 0.87 HPGD (0.50) HPGDGAAMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9006490-B2 Method for direct functionalization of polyaniline and other molecules having diiminoquinoid ring via C-C bond formation Han, Chien-Chung (TW) 2015-04-14 US disclosed
US-20120130114-A1 METHOD FOR DIRECT FUNCTIONALIZATION OF POLYANILINE AND OTHER MOLECULES HAVING DIIMINOQUINOID RING VIA C-C BOND FORMATION, AND PRODUCT YIELDED THEREWITH Han, Chien-Chung (TW) 2012-05-24 US disclosed
US-7630117-B2 Electrolyte comprising eutectic mixture and electrochromic device using the same LG CHEM, LTD. (KR) 2009-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120130114-A1 METHOD FOR DIRECT FUNCTIONALIZATION OF POLYANILINE AND OTHER MOLECULES HAVING DIIMINOQUINOID RING VIA C-C BOND FORMATION, AND PRODUCT YIELDED THEREWITH PAICS, PARG, INF2 HPGD 1610/4885GAA 2630/4885MEN1 130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.