Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417179 | 0.90 | AVPR2 (0.46) | AVPR2AVPR1ALMNATSHRKMT2A | |
| SCHEMBL8228870 | 0.87 | TSHR (0.58) | AVPR2AVPR1ALMNATSHRKMT2A | |
| SCHEMBL2434361 | 0.84 | AVPR2 (0.42) | AVPR2AVPR1ALMNATSHRKMT2A | |
| SCHEMBL2446987 | 0.84 | AVPR2 (0.47) | AVPR2AVPR1ALMNATSHRKMT2A | |
| SCHEMBL2446528 | 0.83 | AVPR2 (0.48) | AVPR2AVPR1ALMNATSHRKMT2A | |
| SCHEMBL4502112 | 0.81 | AVPR2 (0.44) | AVPR2AVPR1ALMNATSHRKMT2A | |
| SCHEMBL8227891 | 0.80 | TP53 (0.51) | KMT2AALDH1A1MAPT | |
| SCHEMBL12503775 | 0.80 | AVPR2 (0.46) | AVPR2AVPR1ALMNATSHRKMT2A | |
| SCHEMBL4491713 | 0.79 | TSHR (0.54) | AVPR2AVPR1ALMNATSHRKMT2A | |
| SCHEMBL8233185 | 0.79 | CNR1 (0.48) | AVPR2AVPR1ALMNATSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027096-B1 | SUBSTITUTED ARYLIMIDAZ0L0NE AND TRIAZ0L0NE AS INHIBITORS OF VASOPRESSIN RECEPTORS | Bayer Pharma AG (DE) | 2012-05-23 | — | — | EP | disclosed |