Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 12/20 | 0.56 |
| ▸ | AVPR1A | P37288 | 12/20 | 0.56 |
| ▸ | CCR1 | P32246 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8237253 | 0.90 | AVPR2 (0.59) | AVPR2AVPR1ACCR1TP53MAPT | |
| SCHEMBL8233415 | 0.89 | AVPR2 (0.60) | AVPR2AVPR1ACCR1TP53MAPT | |
| SCHEMBL3977250 | 0.89 | AVPR2 (0.60) | AVPR2AVPR1ACCR1TP53MAPT | |
| SCHEMBL8235559 | 0.89 | AVPR2 (0.62) | AVPR2AVPR1ACCR1TP53MAPT | |
| SCHEMBL8233190 | 0.88 | AVPR2 (0.56) | AVPR2AVPR1ACCR1TP53MAPT | |
| SCHEMBL8235956 | 0.88 | AVPR2 (0.61) | AVPR2AVPR1ACCR1TP53MAPT | |
| SCHEMBL14476692 | 0.86 | AVPR2 (0.57) | AVPR2AVPR1ACCR1TP53MAPT | |
| SCHEMBL8233286 | 0.86 | AVPR2 (0.63) | AVPR2AVPR1ACCR1TP53 | |
| SCHEMBL4500537 | 0.86 | AVPR2 (0.65) | AVPR2AVPR1ACCR1TP53 | |
| SCHEMBL8232808 | 0.86 | AVPR2 (0.58) | AVPR2AVPR1ACCR1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027096-B1 | SUBSTITUTED ARYLIMIDAZ0L0NE AND TRIAZ0L0NE AS INHIBITORS OF VASOPRESSIN RECEPTORS | Bayer Pharma AG (DE) | 2012-05-23 | — | — | EP | disclosed |