Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 13/20 | 0.53 |
| ▸ | AVPR1A | P37288 | 13/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257237 | 0.85 | AVPR2 (0.70) | AVPR2AVPR1A | |
| SCHEMBL256933 | 0.85 | AVPR2 (0.70) | AVPR2AVPR1A | |
| SCHEMBL256937 | 0.85 | AVPR2 (0.70) | AVPR2AVPR1A | |
| SCHEMBL8227135 | 0.83 | AVPR2 (0.47) | AVPR2AVPR1ATSHRCNR1CYP1A2 | |
| SCHEMBL8233090 | 0.83 | AVPR2 (0.49) | AVPR2AVPR1ATSHRCNR1CYP1A2 | |
| SCHEMBL19577887 | 0.82 | AVPR2 (0.48) | AVPR2AVPR1ATSHRCYP1A2GAA | |
| SCHEMBL8235892 | 0.82 | AVPR2 (0.49) | AVPR2AVPR1ATSHRCNR1CYP1A2 | |
| SCHEMBL19569171 | 0.81 | AVPR2 (0.52) | AVPR2AVPR1ATSHRCNR1 | |
| SCHEMBL8233167 | 0.81 | AVPR2 (0.48) | AVPR2AVPR1ATSHRCNR1CYP1A2 | |
| SCHEMBL19574618 | 0.81 | AVPR2 (0.59) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027096-B1 | SUBSTITUTED ARYLIMIDAZ0L0NE AND TRIAZ0L0NE AS INHIBITORS OF VASOPRESSIN RECEPTORS | Bayer Pharma AG (DE) | 2012-05-23 | — | — | EP | disclosed |