Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 17/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8739241 | 0.87 | EZH2 (0.65) | EZH2MEN1KMT2A | |
| SCHEMBL8738661 | 0.86 | EZH2 (0.64) | EZH2MEN1KMT2A | |
| SCHEMBL8738155 | 0.86 | EZH2 (0.73) | EZH2MEN1KMT2A | |
| SCHEMBL8739691 | 0.85 | EZH2 (0.67) | EZH2MEN1KMT2A | |
| SCHEMBL8739676 | 0.85 | EZH2 (0.62) | EZH2MEN1KMT2A | |
| SCHEMBL8738602 | 0.85 | EZH2 (0.64) | EZH2MEN1KMT2A | |
| SCHEMBL8739671 | 0.84 | EZH2 (0.69) | EZH2MEN1KMT2A | |
| SCHEMBL8739712 | 0.84 | EZH2 (0.81) | EZH2MEN1KMT2A | |
| SCHEMBL8739362 | 0.83 | EZH2 (0.63) | EZH2MEN1KMT2A | |
| SCHEMBL8739238 | 0.83 | EZH2 (0.63) | EZH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068589-A2 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS (US) | 2012-05-24 | — | — | WO | disclosed |