Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 18/20 | 0.60 |
| ▸ | AVPR1A | P37288 | 18/20 | 0.60 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8235588 | 0.93 | AVPR2 (0.59) | AVPR2AVPR1ANR1H2NR1H3CNR1 | |
| SCHEMBL8235014 | 0.92 | AVPR2 (0.58) | AVPR2AVPR1ANR1H2NR1H3CNR1 | |
| SCHEMBL8227362 | 0.88 | AVPR2 (0.60) | AVPR2AVPR1ANR1H2NR1H3CNR1 | |
| SCHEMBL8232587 | 0.87 | AVPR2 (0.58) | AVPR2AVPR1ANR1H2NR1H3CNR1 | |
| SCHEMBL8232897 | 0.87 | AVPR2 (0.57) | AVPR2AVPR1ANR1H2NR1H3CNR1 | |
| SCHEMBL8232603 | 0.87 | AVPR2 (0.57) | AVPR2AVPR1ANR1H2NR1H3CNR1 | |
| SCHEMBL8234745 | 0.85 | AVPR2 (0.53) | AVPR2AVPR1ACNR1 | |
| SCHEMBL19244834 | 0.85 | AVPR2 (0.61) | AVPR2AVPR1ANR1H2NR1H3 | |
| SCHEMBL19244833 | 0.84 | AVPR2 (0.59) | AVPR2AVPR1ANR1H2NR1H3 | |
| SCHEMBL8227858 | 0.84 | AVPR2 (0.68) | AVPR2AVPR1ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027096-B1 | SUBSTITUTED ARYLIMIDAZ0L0NE AND TRIAZ0L0NE AS INHIBITORS OF VASOPRESSIN RECEPTORS | Bayer Pharma AG (DE) | 2012-05-23 | — | — | EP | disclosed |