Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEH1 | O60930 | 1/20 | 0.55 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.50 |
| ▸ | FEN1 | P39748 | 2/20 | 0.50 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.39 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL710689 | 0.86 | ERCC1 (0.62) | RNASEH1ERCC1FEN1ERCC4POLB | |
| SCHEMBL1410 | 0.86 | ERCC1 (0.62) | RNASEH1ERCC1FEN1ERCC4POLB | |
| SCHEMBL29361703 | 0.86 | ERCC1 (0.62) | RNASEH1ERCC1FEN1ERCC4POLB | |
| Water SCHEMBL4444794 | 0.84 | ERCC1 (0.60) | RNASEH1ERCC1FEN1ERCC4POLB | |
| SCHEMBL2824836 | 0.84 | ERCC1 (0.60) | RNASEH1ERCC1FEN1ERCC4POLB | |
| Lithium SCHEMBL1279496 | 0.84 | ERCC1 (0.60) | RNASEH1ERCC1FEN1ERCC4POLB | |
| SCHEMBL1279494 | 0.84 | ERCC1 (0.60) | RNASEH1ERCC1FEN1ERCC4POLB | |
| SCHEMBL28423361 | 0.84 | ERCC1 (0.60) | RNASEH1ERCC1FEN1ERCC4POLB | |
| SCHEMBL2824834 | 0.84 | ERCC1 (0.60) | RNASEH1ERCC1FEN1ERCC4POLB | |
| Ammonia Solution, Strong SCHEMBL8656352 | 0.84 | ERCC1 (0.60) | RNASEH1ERCC1FEN1ERCC4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111286041-A | Demethylated lignin, preparation method thereof and application thereof in phenolic resin adhesive | 南京工业大学 | 2020-06-16 | — | — | CN | disclosed |
| US-9765154-B2 | Phosphohistidine analogs | THE ROCKEFELLER UNIVERSITY (US) | 2017-09-19 | — | — | US | disclosed |
| US-20150344589-A1 | PHOSPHOHISTIDINE ANALOGS | THE ROCKEFELLER UNIVERSITY (US) | 2015-12-03 | — | — | US | disclosed |
| US-9035068-B2 | Phosphohistidine analogs | THE ROCKEFELLER UNIVERSITY (US) | 2015-05-19 | — | — | US | disclosed |
| US-20130260398-A1 | PHOSPHOHISTIDINE ANALOGS | THE ROCKEFELLER UNIVERSITY (US) | 2013-10-03 | — | — | US | disclosed |
| WO-2012040523-A2 | PHOSPHOHISTIDINE ANALOGS | THE ROCKEFELLER UNIVERSITY (US) | 2012-03-29 | — | — | WO | disclosed |
| WO-2008033475-A2 | ACTIVATED CYTOTOXIC COMPOUNDS FOR ATTACHMENT TO TARGETING MOLECULES FOR THE TREATMENT OF MAMMALIAN DISEASE CONDITIONS | ONCONOVA THERAPEUTICS, INC. (US) | 2008-03-20 | — | — | WO | disclosed |
| EP-0393934-B1 | Novel peptides, and antidementia agents containing the same | NIPPON CHEMIPHAR CO (JP) | 1994-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130260398-A1 | PHOSPHOHISTIDINE ANALOGS | PHPT1, PTMS, CHAMP1 | RNASEH1 4222/4885ERCC1 4158/4885FEN1 2060/4885 |
| US-20150344589-A1 | PHOSPHOHISTIDINE ANALOGS | PHPT1, PTMS, CHAMP1 | RNASEH1 4111/4885ERCC1 4216/4885FEN1 2378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.