SCHEMBL8740883

SCHEMBL8740883

Cc1cc(C(O)c2ccccc2)c(O)c(C(O)c2ccccc2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
CYP2C9 P11712 1/20 0.44
KMT2A Q03164 1/20 0.44
MLKL Q8NB16 1/20 0.41
SLC6A4 P31645 3/20 0.39
SLC6A2 P23975 2/20 0.39
SLC6A3 Q01959 2/20 0.39
TACR1 P25103 1/20 0.39
LMNA P02545 2/20 0.39
ESR1 P03372 1/20 0.39
CHRM2 P08172 1/20 0.39
CHRM4 P08173 1/20 0.39
CHRM5 P08912 1/20 0.39
CHRM1 P11229 1/20 0.39
KCNE1 P15382 1/20 0.39
CHRM3 P20309 1/20 0.39
PTGS1 P23219 1/20 0.39
HRH2 P25021 1/20 0.39
HTR2A P28223 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28225283 0.82 SLC6A4 (0.40) MAPTMEN1CYP2C9KMT2ASLC6A4
SCHEMBL30442826 0.81 CHRM1 (0.54) MAPTMEN1CYP2C9KMT2AMLKL
SCHEMBL8498311 0.81 CHRM1 (0.54) MAPTMEN1CYP2C9KMT2AMLKL
SCHEMBL224197 0.80 TYR (0.55) MAPTSLC6A4SLC6A2LMNAESR1
SCHEMBL8740882 0.79 MEN1 (0.41) MAPTMEN1CYP2C9KMT2ALMNA
SCHEMBL14509733 0.78 HTT (0.49) MAPTMEN1CYP2C9KMT2AMLKL
SCHEMBL11793204 0.78 CYP2C9 (0.55) MAPTMEN1CYP2C9KMT2ASLC6A4
SCHEMBL15625201 0.78 TYR (0.53) MAPTSLC6A4SLC6A2LMNAESR1
SCHEMBL7012899 0.77 CHRM1 (0.55) MAPTMEN1CYP2C9KMT2AMLKL
SCHEMBL9885964 0.77 TYR (0.51) MAPTSLC6A4SLC6A2LMNAESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5700620-A POSITIVE PHOTORESIST HAVING HIGH RESOLUTION AND SMALL FILM THICKNESS DEPENDENCE FUJI PHOTO FILM CO., LTD. (JP) 1997-12-23 US disclosed