Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102795 | 0.92 | NPSR1 (0.41) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL8117659 | 0.91 | NPSR1 (0.40) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL9135970 | 0.90 | NPSR1 (0.39) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL9134085 | 0.83 | MAPT (0.39) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7173250 | 0.82 | NPSR1 (0.43) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL12131055 | 0.82 | NPSR1 (0.43) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL6216053 | 0.82 | NPSR1 (0.43) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL5504515 | 0.81 | MAPT (0.40) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL8110603 | 0.81 | MAPT (0.38) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL4567537 | 0.81 | CYP2C9 (0.44) | NPSR1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607942-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |
| US-5416096-A | 7-(1-pyrrolidinyl)-3-quinolone carboxylic acid derivatives as antibacterial agents and feed additives | BAYER AKTIENGESELLSCHAFT (DE) | 1995-05-16 | — | — | US | disclosed |
| US-5059597-A | Animal growth regulators; enterobacter | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-22 | — | — | US | disclosed |
| US-4990517-A | 7-(1-pyrrolidinyl)-3-quinolone- and -naphthyridonecarboxylic acid derivatives as antibacterial agents and feed additives | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |