Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 19/20 | 0.60 |
| ▸ | NPY1R | P25929 | 11/20 | 0.60 |
| ▸ | NPY5R | Q15761 | 10/20 | 0.60 |
| ▸ | NPY2R | P49146 | 7/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350041 | 0.92 | NPY4R (0.57) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29649760 | 0.88 | NPY4R (0.61) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29649734 | 0.88 | NPY4R (0.61) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30081133 | 0.87 | NPY4R (0.61) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29649727 | 0.87 | NPY4R (0.65) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29649769 | 0.87 | NPY4R (0.65) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL9141613 | 0.87 | NPY4R (0.64) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30202407 | 0.87 | NPY4R (0.56) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29559026 | 0.85 | NPY4R (0.60) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30331308 | 0.85 | NPY4R (0.64) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724387-A4 | TREATMENT OF CHRONIC ANTI-INFLAMMATORY DISEASES BY ANGIOTENSION II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1997-06-18 | — | — | EP | disclosed |
| EP-0724387-A1 | TREATMENT OF CHRONIC ANTI-INFLAMMATORY DISEASES BY ANGIOTENSION II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995006410-A1 | TREATMENT OF CHRONIC INFLAMMATORY DISEASES BY ANGIOTENSION II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-03-09 | — | — | WO | disclosed |