Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Thiourea. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiourea SCHEMBL10634208 | 0.96 | — | — | |
| Thiourea SCHEMBL10602981 | 0.92 | — | — | |
| Thiocyanic Acid SCHEMBL5823496 | 0.85 | — | — | |
| Sulfuric Acid SCHEMBL28156968 | 0.81 | BLM (0.38) | — | |
| Guanidine SCHEMBL6364290 | 0.77 | — | — | |
| Thiosemicarbazide SCHEMBL27893133 | 0.76 | — | — | |
| Thiourea SCHEMBL27351654 | 0.75 | — | — | |
| Thiourea SCHEMBL28064431 | 0.75 | — | — | |
| Guanidine SCHEMBL2949590 | 0.74 | — | — | |
| Thiocyanic Acid SCHEMBL374590 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643711-A | SPECTRAL SENSITIZATION USING A SENSITIZING DYE AND A COMPOUND WHICH ACCELERATED ADSORPTION TO THE TABULAR GRAIN; PRESSURE RESISTANCE; PRESSURE RESISTANCE; MATERIALS HANDLING | FUJI PHOTO FILM CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |