Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.42 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739314 | 1.00 | POLB (0.55) | POLBL3MBTL1HPGDHSD11B1KCNQ3 | |
| SCHEMBL744692 | 1.00 | POLB (0.55) | POLBL3MBTL1HPGDHSD11B1KCNQ3 | |
| SCHEMBL15723492 | 1.00 | POLB (0.55) | POLBL3MBTL1HPGDHSD11B1KCNQ3 | |
| SCHEMBL13304687 | 1.00 | POLB (0.55) | POLBL3MBTL1HPGDHSD11B1KCNQ3 | |
| SCHEMBL15057174 | 1.00 | POLB (0.55) | POLBL3MBTL1HPGDHSD11B1KCNQ3 | |
| SCHEMBL18629176 | 1.00 | POLB (0.55) | POLBL3MBTL1HPGDHSD11B1KCNQ3 | |
| SCHEMBL18628994 | 1.00 | POLB (0.55) | POLBL3MBTL1HPGDHSD11B1KCNQ3 | |
| SCHEMBL8742210 | 1.00 | POLB (0.55) | POLBL3MBTL1HPGDHSD11B1KCNQ3 | |
| SCHEMBL13012405 | 1.00 | POLB (0.55) | POLBL3MBTL1HPGDHSD11B1KCNQ3 | |
| SCHEMBL222539 | 1.00 | POLB (0.55) | POLBL3MBTL1HPGDHSD11B1KCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624941-A | Pyrazole derivatives, method of preparing them and pharmaceutical compositions in which they are present | SANOFI (FR) | 1997-04-29 | — | — | US | disclosed |