SCHEMBL8743004

SCHEMBL8743004

O=Cc1sc(N=NNc2ccccc2)nc1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 13/20 0.56
KMT2A Q03164 13/20 0.56
MAPT P10636 12/20 0.56
LMNA P02545 4/20 0.56
PSMD14 O00487 3/20 0.56
CYP1A1 P04798 1/20 0.40
TSHR P16473 1/20 0.40
CYP1B1 Q16678 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 4/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
GLA P06280 1/20 0.40
POLB P06746 3/20 0.38
KDM4E B2RXH2 3/20 0.38
RAB9A P51151 7/20 0.36
NPC1 O15118 5/20 0.36
CASP3 P42574 3/20 0.36
SENP7 Q9BQF6 3/20 0.36
SENP8 Q96LD8 2/20 0.36
SENP6 Q9GZR1 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8743006 0.76 MEN1 (0.50) MEN1KMT2AMAPTLMNAPSMD14
SCHEMBL9155775 0.72 MAPT (0.46) MEN1KMT2AMAPTLMNAPSMD14
SCHEMBL7756093 0.72 MAPT (1.00) MEN1KMT2AMAPTLMNAPSMD14
SCHEMBL8991872 0.71 TDP1 (0.42) MEN1KMT2AMAPTLMNAPSMD14
SCHEMBL8767775 0.69 NPC1 (0.54) MEN1KMT2AMAPTLMNACYP1A1
SCHEMBL8742825 0.69 MEN1 (0.36) MEN1KMT2AMAPTLMNAPSMD14
SCHEMBL29956125 0.66 MEN1 (0.55) MEN1KMT2AMAPTLMNAPSMD14
SCHEMBL13390353 0.63 MAPT (0.44) MEN1KMT2AMAPTLMNAPSMD14
SCHEMBL15331855 0.63 MAPT (0.51) MEN1KMT2AMAPTLMNAPSMD14
SCHEMBL29956897 0.63 KMT2A (0.55) MEN1KMT2AMAPTLMNAPSMD14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0579297-B1 Dye-donor element for use in thermal dye transfer by sublimation AGFA GEVAERT NV (BE) 1997-01-02 EP claimed
US-5510225-A CONTAINS ANILINE AZO DYE IN A DYE LAYER CARRIED BY POLYMERIC BINDER RESIN ON A SUPPORT AGFA-GEVAERT, N.V. (BE) 1996-04-23 US claimed
EP-0522207-B1 Thermal dye transfer printing method and dye-donor element for use according to said method AGFA GEVAERT NV (BE) 1995-10-18 EP claimed
EP-0453020-B1 Black colored thermal dye sublimation transfer donor element AGFA GEVAERT NV (BE) 1995-01-18 EP claimed
EP-0579297-A1 Dye-donor element for use in thermal dye transfer by sublimation AGFA-GEVAERT N.V. (BE) 1994-01-19 EP claimed
WO-1993010978-A1 METHOD OF MAKING A MONOCHROMIC COLOURED THERMAL DYE IMAGE AGFA-GEVAERT NAAMLOZE VENNOOTSCHAP (BE) 1993-06-10 WO claimed
EP-0522207-A1 Thermal dye transfer printing method and dye-donor element for use according to said method AGFA-GEVAERT N.V. (BE) 1993-01-13 EP claimed
US-5169828-A Support with dye layer containing mixture of yellow dye and another dye; uniform high density images AGFA-GEVAERT, N.V. (BE) 1992-12-08 US claimed
EP-0453020-A1 Black colored thermal dye sublimation transfer donor element AGFA-GEVAERT N.V. (BE) 1991-10-23 EP claimed
JP-4226393-A None JP disclosed
US-5616697-A THIAZOLYL RING CONTAINS A SUBSTITUENT SELECTED FORM HYDROXY, ALKOXY, CYCLOALKOXY, ARYLOXY, MERCAPTO, THIOALKYL, THIOCYCLOALKYL AND THIOARYL AT 4-POSITION AGFA-GEVAERT, N.V. (BE) 1997-04-01 US disclosed
EP-0579299-B1 Black colored dye mixture for use according to thermal dye sublimation transfer AGFA GEVAERT NV (BE) 1997-01-02 EP disclosed
EP-0579297-B1 Dye-donor element for use in thermal dye transfer by sublimation AGFA GEVAERT NV (BE) 1997-01-02 EP disclosed
EP-0578870-B1 Thiazolylazoaniline dyes for use in thermal dye sublimation transfer AGFA GEVAERT NV (BE) 1996-12-11 EP disclosed
EP-0522207-A1 Thermal dye transfer printing method and dye-donor element for use according to said method AGFA-GEVAERT N.V. (BE) 1993-01-13 EP disclosed
US-5169828-A Support with dye layer containing mixture of yellow dye and another dye; uniform high density images AGFA-GEVAERT, N.V. (BE) 1992-12-08 US disclosed
US-5169828-A Support with dye layer containing mixture of yellow dye and another dye; uniform high density images AGFA-GEVAERT, N.V. (BE) 1992-12-08 US disclosed
JP-H04226393-A BLACK COLORED THERMAL DYE SUBLIMATION TRANSFER DONOR MATERIAL AGFA GEVAERT NV 1992-08-17 JP disclosed
EP-0453020-A1 Black colored thermal dye sublimation transfer donor element AGFA-GEVAERT N.V. (BE) 1991-10-23 EP disclosed
EP-0453020-A1 Black colored thermal dye sublimation transfer donor element AGFA-GEVAERT N.V. (BE) 1991-10-23 EP disclosed