Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 4/20 | 0.80 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8743215 | 1.00 | TBXA2R (0.80) | TBXA2RTBXAS1SLC6A3KCNH2LMNA | |
| SCHEMBL8742878 | 0.86 | TBXA2R (0.59) | TBXA2RKCNH2 | |
| SCHEMBL8742870 | 0.86 | TBXA2R (0.59) | TBXA2RKCNH2 | |
| SCHEMBL9699510 | 0.85 | TBXA2R (0.82) | TBXA2RTBXAS1SLC6A3KCNH2LMNA | |
| SCHEMBL8743288 | 0.84 | TBXA2R (0.80) | TBXA2RTBXAS1SLC6A3KCNH2LMNA | |
| SCHEMBL8743284 | 0.84 | TBXA2R (0.80) | TBXA2RTBXAS1SLC6A3KCNH2LMNA | |
| SCHEMBL9700590 | 0.84 | TBXA2R (0.76) | TBXA2RTBXAS1SLC6A3KCNH2LMNA | |
| SCHEMBL8742842 | 0.83 | TBXA2R (0.75) | TBXA2RTBXAS1SLC6A3KCNH2LMNA | |
| SCHEMBL8742932 | 0.83 | TBXA2R (1.00) | TBXA2RTBXAS1SLC6A3KCNH2LMNA | |
| SCHEMBL8742836 | 0.83 | TBXA2R (0.75) | TBXA2RTBXAS1SLC6A3KCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354913-A | Chemical intermediates for drugs or drugs as thromboxane, prostaglandin antagonist, lipoxygenase enzyme inhibitor, antioxidants | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-11 | — | — | US | claimed |
| EP-0751113-A1 | Optically active phenol derivatives and preparation thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5420363-A | Catalytic reaction of phenol with secondary carbinol for enantiomorphs | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| US-5354913-A | Chemical intermediates for drugs or drugs as thromboxane, prostaglandin antagonist, lipoxygenase enzyme inhibitor, antioxidants | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0582382-A2 | Optically active phenol derivatives and preparation thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-02-09 | — | — | EP | disclosed |