Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4297794 | 0.81 | MEN1 (0.71) | KMT2AMEN1TSHRMAPK1HIF1A | |
| SCHEMBL26402 | 0.81 | MEN1 (1.00) | KMT2AMEN1TSHRMAPK1HIF1A | |
| SCHEMBL1016971 | 0.81 | KMT2A (0.71) | KMT2AMEN1TSHRMAPK1HIF1A | |
| SCHEMBL11797483 | 0.78 | TSHR (0.67) | KMT2AMEN1TSHRMAPK1HIF1A | |
| SCHEMBL83653 | 0.78 | MEN1 (0.59) | KMT2AMEN1TSHRMAPK1HIF1A | |
| SCHEMBL677101 | 0.78 | MEN1 (0.59) | KMT2AMEN1TSHRMAPK1HIF1A | |
| SCHEMBL8322314 | 0.78 | MEN1 (0.59) | KMT2AMEN1TSHRMAPK1HIF1A | |
| SCHEMBL2860836 | 0.77 | TSHR (0.74) | KMT2AMEN1TSHRMAPK1HIF1A | |
| Phenaglycodol SCHEMBL259155 | 0.77 | MEN1 (0.65) | KMT2AMEN1TSHRMAPK1HIF1A | |
| Dicofol SCHEMBL10811113 | 0.77 | TSHR (0.90) | KMT2AMEN1TSHRMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101243040-B | Synthesis method of mandipropamid and derivatives thereof | SYNGENTA PARTICIPATIONS AG | 2012-12-05 | — | — | CN | disclosed |
| CN-101243040-A | Synthesis method of mandipropamid and derivatives thereof | SYNGENTA PARTICIPATIONS AG (CH) | 2008-08-13 | — | — | CN | disclosed |
| US-5677168-A | Enantiomeric separation of (RS)1-(4-chlorophenyl)-2-chloroethanol by lipase catalyzed hydrolysis of its acetate | SYNTHELABO (FR) | 1997-10-14 | — | — | US | disclosed |