Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 9/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL757909 | 1.00 | EPHX2 (0.54) | EPHX2PPARAS1PR2S1PR1S1PR3 | |
| SCHEMBL757911 | 1.00 | EPHX2 (0.54) | EPHX2PPARAS1PR2S1PR1S1PR3 | |
| SCHEMBL29714277 | 0.98 | EPHX2 (0.52) | EPHX2PPARAS1PR2S1PR1S1PR3 | |
| SCHEMBL30238243 | 0.98 | EPHX2 (0.52) | EPHX2PPARAS1PR2S1PR1S1PR3 | |
| SCHEMBL8388884 | 0.98 | EPHX2 (0.52) | EPHX2PPARAS1PR2S1PR1S1PR3 | |
| SCHEMBL180860 | 0.98 | EPHX2 (0.52) | EPHX2PPARAS1PR2S1PR1S1PR3 | |
| SCHEMBL128136 | 0.98 | EPHX2 (0.52) | EPHX2PPARAS1PR2S1PR1S1PR3 | |
| SCHEMBL4096856 | 0.98 | EPHX2 (0.52) | EPHX2PPARAS1PR2S1PR1S1PR3 | |
| Sulfuric Acid SCHEMBL17743520 | 0.90 | EPHX2 (0.51) | EPHX2PPARAS1PR2S1PR1S1PR3 | |
| Sulfuric Acid SCHEMBL17743518 | 0.90 | EPHX2 (0.51) | EPHX2PPARAS1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0342633-B1 | Transformation du Bacillus thuringiensis | CIBA GEIGY AG (CH) | 1997-01-08 | — | — | EP | disclosed |
| EP-0238441-B1 | Insecticidal proteinaceous substance | CIBA GEIGY AG (CH) | 1993-11-10 | — | — | EP | disclosed |
| EP-0440581-A1 | Temperature stable bacillus thuringiensis-toxin | CIBA-GEIGY AG (CH) | 1991-08-07 | — | — | EP | disclosed |
| EP-0238441-A2 | Insecticidal proteinaceous substance | CIBA-GEIGY AG (CH) | 1987-09-23 | — | — | EP | disclosed |