Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20120334 | 0.90 | KMT2A (0.36) | MEN1KMT2AL3MBTL1KDM4C | |
| SCHEMBL20213991 | 0.90 | KMT2A (0.36) | MEN1KMT2AL3MBTL1KDM4C | |
| SCHEMBL9156540 | 0.86 | MEN1 (0.37) | MEN1KMT2AL3MBTL1KDM4C | |
| SCHEMBL17678845 | 0.79 | MEN1 (0.34) | MEN1KMT2AL3MBTL1KDM4C | |
| SCHEMBL8572408 | 0.78 | MEN1 (0.37) | MEN1KMT2AL3MBTL1KDM4C | |
| SCHEMBL20120633 | 0.77 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL30679074 | 0.77 | MEN1 (0.41) | MEN1KMT2AL3MBTL1KDM4C | |
| SCHEMBL22436681 | 0.77 | MEN1 (0.41) | MEN1KMT2AL3MBTL1KDM4C | |
| SCHEMBL27098751 | 0.76 | MEN1 (0.33) | MEN1KMT2AL3MBTL1KDM4C | |
| SCHEMBL20120528 | 0.76 | MEN1 (0.37) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335770-B1 | Novel fluorophosphonate nucleotide derivatives | MERRELL PHARMA INC (US) | 1997-01-15 | — | — | EP | disclosed |
| EP-0339161-A1 | Novel fluorophosphonate nucleotide derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-11-02 | — | — | EP | disclosed |
| EP-0335770-A2 | Novel fluorophosphonate nucleotide derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1989-10-04 | — | — | EP | disclosed |