SCHEMBL8743648

SCHEMBL8743648

CC(C)(C)NC1=[C]CC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8088828 0.73
SCHEMBL6434247 0.64
SCHEMBL620282 0.59
SCHEMBL3051777 0.58
SCHEMBL7785766 0.58
SCHEMBL12203150 0.57 SMN1; SMN2 (0.32)
SCHEMBL15828761 0.55
SCHEMBL2850639 0.54
SCHEMBL10586720 0.54
SCHEMBL8159879 0.54

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0750625-A1 PREPARATION OF MONOCYCLOPENTADIENYL METAL COMPLEXES BY NUCLEOPHILIC SUBSTITUTION OF BIS(CYCLOPENTADIENYL) METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 1997-01-02 EP disclosed
WO-1995025112-A1 PREPARATION OF MONOCYCLOPENTADIENYL METAL COMPLEXES BY NUCLEOPHILIC SUBSTITUTION OF BIS(CYCLOPENTADIENYL) METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 1995-09-21 WO disclosed
EP-0416815-A2 Constrained geometry addition polymerization catalysts, processes for their preparation, precursors therefor, methods of use, and novel polymers formed therewith THE DOW CHEMICAL COMPANY (US) 1991-03-13 EP disclosed