Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25633681 | 0.73 | PRSS1 (0.68) | PRSS1PRSS2PRSS3ALDH1A1CA2 | |
| SCHEMBL25633666 | 0.73 | PRSS1 (0.68) | PRSS1PRSS2PRSS3ALDH1A1CA2 | |
| SCHEMBL25633652 | 0.73 | PRSS1 (0.68) | PRSS1PRSS2PRSS3ALDH1A1CA2 | |
| SCHEMBL28256770 | 0.70 | PRSS1 (0.89) | PRSS1PRSS2PRSS3ALDH1A1CA2 | |
| SCHEMBL30863762 | 0.69 | PRSS1 (0.86) | PRSS1PRSS2PRSS3ALDH1A1CA2 | |
| SCHEMBL3221063 | 0.69 | PRSS1 (0.86) | PRSS1PRSS2PRSS3ALDH1A1CA2 | |
| SCHEMBL31285744 | 0.69 | PRSS1 (0.62) | PRSS1PRSS2PRSS3ALDH1A1CA2 | |
| SCHEMBL21296373 | 0.69 | PRSS1 (0.75) | PRSS1PRSS2PRSS3ALDH1A1CA2 | |
| SCHEMBL1417231 | 0.68 | PRSS1 (0.62) | PRSS1PRSS2PRSS3ALDH1A1CA2 | |
| SCHEMBL30849898 | 0.68 | PRSS1 (0.84) | PRSS1PRSS2PRSS3ALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739054-A | FOR METALS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-04-19 | — | — | US | claimed |
| EP-0753078-A1 | SOLVENT EXTRACTION PROCESS | ZENECA LIMITED (GB) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995027085-A1 | SOLVENT EXTRACTION PROCESS | ZENECA LIMITED (GB) | 1995-10-12 | — | — | WO | disclosed |