⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851977 | 1.00 | — | — | |
| SCHEMBL17136878 | 1.00 | — | — | |
| SCHEMBL9851975 | 1.00 | — | — | |
| SCHEMBL23189070 | 0.82 | — | — | |
| SCHEMBL367376 | 0.82 | — | — | |
| SCHEMBL14749809 | 0.82 | — | — | |
| SCHEMBL367375 | 0.82 | — | — | |
| SCHEMBL18543204 | 0.78 | — | — | |
| SCHEMBL29261199 | 0.78 | — | — | |
| SCHEMBL25100201 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537606-B1 | Process for the preparation of 5-hydroxyethylpyrrolidones | BASF AG (DE) | 1997-01-29 | — | — | EP | claimed |
| US-5286875-A | Preparation of 5-hydroxyethylpyrrolidones | BASF AKTIENGESELLSCHAFT (DE) | 1994-02-15 | — | — | US | claimed |
| WO-2022132686-A1 | FUSED BICYCLIC PYRAZOLE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF HERPESVIRUSES | MERCK SHARP & DOHME CORP. (US) | 2022-06-23 | — | — | WO | disclosed |
| EP-3305900-B1 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | NUEVOLUTION AS (DK) | 2021-07-21 | — | — | EP | disclosed |
| US-20120100274-A1 | METHOD FOR SYNTHESISING 2-ACETYL-1-PYRROLINE AND THE STABLE PRECURSOR THEREOF, OPTIONALLY ISOTOPICALLY MARKED | UNIVERSITE DE MONTPELLIER (FR) | 2012-04-26 | — | — | US | disclosed |
| US-20120100274-A1 | METHOD FOR SYNTHESISING 2-ACETYL-1-PYRROLINE AND THE STABLE PRECURSOR THEREOF, OPTIONALLY ISOTOPICALLY MARKED | UNIVERSITE DE MONTPELLIER (FR) | 2012-04-26 | — | — | US | disclosed |
| EP-0537606-B1 | Process for the preparation of 5-hydroxyethylpyrrolidones | BASF AG (DE) | 1997-01-29 | — | — | EP | disclosed |
| EP-0537606-B1 | Process for the preparation of 5-hydroxyethylpyrrolidones | BASF AG (DE) | 1997-01-29 | — | — | EP | disclosed |
| US-5286875-A | Preparation of 5-hydroxyethylpyrrolidones | BASF AKTIENGESELLSCHAFT (DE) | 1994-02-15 | — | — | US | disclosed |
| US-5286875-A | Preparation of 5-hydroxyethylpyrrolidones | BASF AKTIENGESELLSCHAFT (DE) | 1994-02-15 | — | — | US | disclosed |
| US-5286875-A | Preparation of 5-hydroxyethylpyrrolidones | BASF AKTIENGESELLSCHAFT (DE) | 1994-02-15 | — | — | US | disclosed |
| EP-0537606-A1 | Process for the preparation of 5-hydroxyethylpyrrolidones | BASF Aktiengesellschaft (DE) | 1993-04-21 | — | — | EP | disclosed |
| EP-0537606-A1 | Process for the preparation of 5-hydroxyethylpyrrolidones | BASF Aktiengesellschaft (DE) | 1993-04-21 | — | — | EP | disclosed |
| EP-0537606-A1 | Process for the preparation of 5-hydroxyethylpyrrolidones | BASF Aktiengesellschaft (DE) | 1993-04-21 | — | — | EP | disclosed |