SCHEMBL874522

SCHEMBL874522

NC1CC=C(C(=O)O)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL692857 1.00
SCHEMBL691945 1.00
Hydrochloric Acid SCHEMBL22711535 0.98 GABRR1 (0.96)
SCHEMBL4077485 0.82 GABRR1 (0.69)
SCHEMBL22659954 0.82
SCHEMBL19506521 0.78 GABRR1 (0.64)
SCHEMBL6255571 0.78 GABRR1 (0.64)
SCHEMBL23299695 0.77 GABRR1 (0.62)
SCHEMBL22659291 0.77 GABRR1 (1.00)
SCHEMBL13046000 0.77 GABRR1 (0.62)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240092849-A1 SELECTIVE MCL-1 BINDING PEPTIDES MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2024-03-21 US claimed
US-20190077840-A1 SELECTIVE MCL-1 BINDING PEPTIDES NATIONAL INSTITUTES OF HEALTH 2019-03-14 US claimed
WO-2017075349-A2 SELECTIVE MCL-1 BINDING PEPTIDES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-05-04 WO claimed
US-5688933-A Preparation of biologically active compounds from substantially pure enantiomers of 2-azabicyclo 2.2.1!hept-5-en-one CHIROSCIENCE, LTD. (GB) 1997-11-18 US claimed
EP-4745152-A2 PEPTIDES BINDING TO BFL-1 Dana-Farber Cancer Institute, Inc. (US) 2026-05-20 EP disclosed
EP-3341008-B1 PEPTIDES BINDING TO BFL-1 DANA FARBER CANCER INST INC (US) 2026-04-15 EP disclosed
US-12570698-B2 Stabilized peptides for covalent binding to target protein DANA-FARBER CANCER INSTITUTE, INC. (US) 2026-03-10 US disclosed
US-12552834-B2 Selective MENA binding peptides MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2026-02-17 US disclosed
US-20260035421-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF FOXP3 UNIV CHICAGO (US) 2026-02-05 US disclosed
US-12528846-B2 BH4 stabilized peptides and uses thereof DANA-FARBER CANCER INSTITUTE, INC. (US) 2026-01-20 US disclosed
US-20250368694-A1 SELECTIVE TARGETING OF UBIQUITIN- AND UBIQUITIN-LIKE E1-ACTIVATING ENZYMES BY STRUCTURALLY-STABILIZED PEPTIDES DANA FARBER CANCER INST INC (US) 2025-12-04 US disclosed
US-12466853-B2 Selective targeting of apoptosis proteins by structurally-stabilized and/or cysteine-reactive NOXA peptides DANA-FARBER CANCER INSTITUTE, INC. (US) 2025-11-11 US disclosed
WO-2012040459-A2 BETA-CATENIN TARGETING PEPTIDES AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2012-03-29 WO disclosed
EP-2356139-A2 LIGATION OF STAPLED POLYPEPTIDES President and Fellows of Harvard College (US) 2011-08-17 EP disclosed
US-20110144306-A1 LIGATION OF STAPLED POLYPEPTIDES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2011-06-16 US disclosed
WO-2011008260-A2 BIFUNCTIONAL STAPLED POLYPEPTIDES AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2011-01-20 WO disclosed
US-20100184645-A1 STITCHED POLYPEPTIDES PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2010-07-22 US disclosed
WO-2010011313-A2 LIGATION OF STAPLED POLYPEPTIDES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2010-01-28 WO disclosed
EP-2142562-A2 STITCHED POLYPEPTIDES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2010-01-13 EP disclosed
WO-2008121767-A2 STITCHED POLYPEPTIDES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2008-10-09 WO disclosed