⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6429497 | 0.94 | — | — | |
| SCHEMBL9465483 | 0.86 | — | — | |
| SCHEMBL8745303 | 0.85 | — | — | |
| SCHEMBL8767489 | 0.79 | — | — | |
| SCHEMBL9166487 | 0.77 | — | — | |
| SCHEMBL5996900 | 0.75 | — | — | |
| SCHEMBL8057325 | 0.74 | — | — | |
| SCHEMBL9171155 | 0.72 | — | — | |
| SCHEMBL8768730 | 0.72 | — | — | |
| SCHEMBL9171663 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0662954-B1 | NOVEL VITAMIN D ANALOGUES | LEO PHARM PROD LTD (DK) | 1997-08-20 | — | — | EP | disclosed |
| EP-0675878-B1 | NOVEL VITAMIN D ANALOGUES | LEO PHARM PROD LTD (DK) | 1997-01-29 | — | — | EP | disclosed |
| US-5589471-A | Vitamin D analogues containing a hydroxy or alkylated hydroxy group in the 20-position | FABRIK PRODUKTIONSAKTIESELSKAB LEO PHARMACEUTICAL PRODUCTS LTD. (DK) | 1996-12-31 | — | — | US | disclosed |
| US-5554599-A | ANTIINFLAMMATORY AND IMMUNOMODULATING AGENTS; PSORIASIS, OSTEOPOROSIS, OSTEOGENESIS | LEO PHARMACEUTICAL PRODUCTS LTD. (DK) | 1996-09-10 | — | — | US | disclosed |
| US-5447924-A | Vitamin D analogues | LEO PHARMACEUTICAL PRODUCTS LTD. (DK) | 1995-09-05 | — | — | US | disclosed |
| US-5401732-A | Autoimmune diseases | LEO PHARMACEUTICAL PRODUCTS LTD. A/S KEMISKE FABRIK PRODUKIONSAKTIESE SKAB (DK) | 1995-03-28 | — | — | US | disclosed |
| EP-0543864-B1 | NOVEL VITAMIN D ANALOGUES | LEO PHARM PROD LTD (DK) | 1994-12-14 | — | — | EP | disclosed |
| EP-0460032-B1 | NOVEL VITAMIN D ANALOGUES | LEO PHARM PROD LTD (DK) | 1994-04-27 | — | — | EP | disclosed |
| EP-0412110-B1 | NOVEL VITAMIN D ANALOGUES | LEO PHARM PROD LTD (DK) | 1993-07-07 | — | — | EP | disclosed |
| EP-0543864-A1 | NOVEL VITAMIN D ANALOGUES. | LEO PHARM PROD LTD (DK) | 1993-06-02 | — | — | EP | disclosed |
| US-5206229-A | Inhibit cell proliferation, antiinflammatory, treating imbalance of immune system | LEO PHARMACEUTICAL PRODUCTS LTD (DK) | 1993-04-27 | — | — | US | disclosed |
| WO-1992003414-A1 | NOVEL VITAMIN D ANALOGUES | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 1992-03-05 | — | — | WO | disclosed |
| EP-0412110-A1 | NOVEL VITAMIN D ANALOGUES. | LEO PHARM PROD LTD (DK) | 1991-02-13 | — | — | EP | disclosed |
| WO-1989010351-A1 | NOVEL VITAMIN D ANALOGUES | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LØVENS KEMIS (DK) | 1989-11-02 | — | — | WO | disclosed |