Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10350025 | 0.99 | MAPT (0.35) | CYP2C9KDM1AMAPTARCHEK1 | |
| SCHEMBL10484059 | 0.99 | MAPT (0.35) | CYP2C9KDM1AMAPTARCHEK1 | |
| SCHEMBL10350024 | 0.99 | MAPT (0.35) | CYP2C9KDM1AMAPTARCHEK1 | |
| SCHEMBL10484068 | 0.99 | MAPT (0.35) | CYP2C9KDM1AMAPTARCHEK1 | |
| SCHEMBL9416896 | 0.96 | CYP2C9 (0.35) | CYP2C9KDM1AMAPTARCHEK1 | |
| SCHEMBL9416894 | 0.96 | CYP2C9 (0.35) | CYP2C9KDM1AMAPTARCHEK1 | |
| SCHEMBL9344768 | 0.96 | CYP2C9 (0.36) | CYP2C9KDM1AMAPTARCHEK1 | |
| SCHEMBL8077024 | 0.96 | CYP2C9 (0.36) | CYP2C9KDM1AMAPTARCHEK1 | |
| SCHEMBL17190567 | 0.95 | MAPT (0.37) | CYP2C9KDM1AMAPTARCHEK1 | |
| SCHEMBL5886452 | 0.95 | MAPT (0.37) | CYP2C9KDM1AMAPTARCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563981-B1 | Cis-1,4-substituted 2-butene derivative | CHISSO CORP (JP) | 1997-01-22 | — | — | EP | disclosed |
| EP-0205503-A1 | LIQUID CRYSTALLINE PHASE. | MERCK PATENT GMBH (DE) | 1986-12-30 | — | — | EP | disclosed |
| WO-1986003769-A1 | LIQUID CRYSTALLINE PHASE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-07-03 | — | — | WO | disclosed |