Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCNA | P12004 | 2/20 | 0.58 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745404 | 1.00 | PCNA (0.58) | PCNASLC7A5PPARGMEN1KMT2A | |
| SCHEMBL28502876 | 0.88 | SLC7A5 (0.62) | PCNASLC7A5PPARGMEN1KMT2A | |
| SCHEMBL28502877 | 0.88 | SLC7A5 (0.62) | PCNASLC7A5PPARGMEN1KMT2A | |
| SCHEMBL30114468 | 0.85 | MEN1 (0.77) | PCNASLC7A5PPARGMEN1KMT2A | |
| SCHEMBL677650 | 0.85 | MEN1 (0.77) | PCNASLC7A5PPARGMEN1KMT2A | |
| SCHEMBL29397778 | 0.85 | MEN1 (0.77) | PCNASLC7A5PPARGMEN1KMT2A | |
| SCHEMBL8329881 | 0.85 | MEN1 (0.77) | PCNASLC7A5PPARGMEN1KMT2A | |
| SCHEMBL1170097 | 0.85 | MEN1 (0.77) | PCNASLC7A5PPARGMEN1KMT2A | |
| SCHEMBL8745418 | 0.84 | PCNA (0.72) | PCNASLC7A5PPARGMEN1KMT2A | |
| SCHEMBL7630334 | 0.84 | PCNA (0.72) | PCNASLC7A5PPARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612308-B1 | METHOD FOR PREPARING RADIO-IODINATED THYRONINE DERIVATIVES; NOVEL INTERMEDIATES | HENNING BERLIN GMBH (DE) | 1997-02-05 | — | — | EP | disclosed |
| EP-0612308-A1 | METHOD FOR PREPARING RADIO-IODINATED THYRONINE DERIVATIVES; NOVEL INTERMEDIATES. | HENNING BERLIN GMBH (DE) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993009076-A1 | METHOD FOR PREPARING RADIO-IODINATED THYRONINE DERIVATIVES; NOVEL INTERMEDIATES | HENNING BERLIN GMBH CHEMIE- UND PHARMAWERK (DE) | 1993-05-13 | — | — | WO | disclosed |