Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.66 |
| ▸ | PGR | P06401 | 2/20 | 0.66 |
| ▸ | AR | P10275 | 2/20 | 0.66 |
| ▸ | EGFR | P00533 | 1/20 | 0.66 |
| ▸ | LCK | P06239 | 1/20 | 0.66 |
| ▸ | FYN | P06241 | 1/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.66 |
| ▸ | DRD1 | P21728 | 1/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | HRH2 | P25021 | 1/20 | 0.66 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.66 |
| ▸ | PDE4A | P27815 | 1/20 | 0.66 |
| ▸ | HTR2A | P28223 | 1/20 | 0.66 |
| ▸ | HTR2C | P28335 | 1/20 | 0.66 |
| ▸ | DRD3 | P35462 | 1/20 | 0.66 |
| ▸ | HTR2B | P41595 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745521 | 1.00 | KCNH2 (0.66) | KCNH2PGRAREGFRLCK | |
| Hydrochloric Acid SCHEMBL31690230 | 0.99 | KCNH2 (0.66) | KCNH2PGRAREGFRLCK | |
| Hydrochloric Acid SCHEMBL5824121 | 0.99 | KCNH2 (0.66) | KCNH2PGRAREGFRLCK | |
| Hydrochloric Acid SCHEMBL718536 | 0.99 | KCNH2 (0.65) | KCNH2PGRAREGFRLCK | |
| SCHEMBL9227982 | 0.90 | KCNH2 (0.64) | KCNH2PGRAREGFRLCK | |
| SCHEMBL9227984 | 0.90 | KCNH2 (0.64) | KCNH2PGRAREGFRLCK | |
| SCHEMBL9200483 | 0.90 | KCNH2 (0.72) | KCNH2PGRAREGFRLCK | |
| SCHEMBL9200472 | 0.90 | KCNH2 (0.72) | KCNH2PGRAREGFRLCK | |
| SCHEMBL7524804 | 0.89 | KCNH2 (0.71) | KCNH2PGRAREGFRLCK | |
| Hydrochloric Acid SCHEMBL9210207 | 0.89 | KCNH2 (0.71) | KCNH2PGRAREGFRLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389368-B1 | New derivatives of 6-(1-piperazinyl) 2,5-pyridine diamine N,N,N',N'-substituted, procedure for their production and intermediates, their use as medicines and pharmaceutical preparations containing them | ROUSSEL UCLAF (FR) | 1997-01-29 | — | — | EP | claimed |
| US-5538721-A | LIGHTLY CROSSLINKED CARBOXY POLYMER | INSITE VISION INCORPORATED (US) | 1996-07-23 | — | — | US | claimed |
| WO-1992018089-A2 | USE OF STEROIDAL AND NON-STEROIDAL AMINES TO SENSITIZE MULTIDRUG-RESISTANT CELLS | THE UPJOHN COMPANY (US) | 1992-10-29 | — | — | WO | claimed |
| EP-0238545-A1 | C 20? THROUGH C 26? AMINO STEROIDS. | UPJOHN CO (US) | 1987-09-30 | — | — | EP | claimed |
| WO-1987001706-A2 | C20 THROUGH C26 AMINO STEROIDS | THE UPJOHN COMPANY (US) | 1987-03-26 | — | — | WO | claimed |
| EP-0389368-B1 | New derivatives of 6-(1-piperazinyl) 2,5-pyridine diamine N,N,N',N'-substituted, procedure for their production and intermediates, their use as medicines and pharmaceutical preparations containing them | ROUSSEL UCLAF (FR) | 1997-01-29 | — | — | EP | disclosed |
| US-5506354-A | ANTIULCER, ANTITURMOR, ANTIARTHRITIC, ANTIATHEROSCLEROSIS, ANTIALLERGIC, ANTIASTHMA AGENTS | THE UPJOHN COMPANY (US) | 1996-04-09 | — | — | US | disclosed |
| EP-0238545-B1 | C20 THROUGH C26 AMINO STEROIDS | UPJOHN CO (US) | 1995-11-15 | — | — | EP | disclosed |
| US-RE35053-E | Intermediates for amino substituted steroids | THE UPJOHN COMPANY (US) | 1995-10-10 | — | — | US | disclosed |
| EP-0263213-B1 | C20 Through C26 amino steroids | UPJOHN CO (US) | 1995-09-06 | — | — | EP | disclosed |
| US-5436337-A | Anticarcinogenic agents | THE UPJOHN COMPANY (US) | 1995-07-25 | — | — | US | disclosed |
| US-5382661-A | Useful in treating spinal trauma, head injury, subarachnoid hemorrhage | THE UPJOHN COMPANY (US) | 1995-01-17 | — | — | US | disclosed |
| US-5322943-A | As substituents on steroids are useful as pharmaceutical agents for treating a number of conditions | THE UPJOHN COMPANY (US) | 1994-06-21 | — | — | US | disclosed |
| US-5268477-A | Containing a pyrrolidine or pyridine ring structure | THE UPJOHN COMPANY (US) | 1993-12-07 | — | — | US | disclosed |
| US-5175281-A | Antiulcer, antiinflammatory, antiischemic, antiallergen, antisecretory, wound healing agents; cardiovascular disorders | THE UPJOHN COMPANY (US) | 1992-12-29 | — | — | US | disclosed |
| US-5099019-A | Central nervous system steroid derivative drugs | UPJOHN COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0389368-A1 | New derivatives of 6-(1-piperazinyl) 2,5-pyridine diamine N,N,N',N'-substituted, procedure for their production and intermediates, their use as medicines and pharmaceutical preparations containing them | ROUSSEL UCLAF (FR) | 1990-09-26 | — | — | EP | disclosed |
| EP-0263213-A1 | C20 Through C26 amino steroids | THE UPJOHN COMPANY (US) | 1988-04-13 | — | — | EP | disclosed |
| EP-0238545-A1 | C 20? THROUGH C 26? AMINO STEROIDS. | UPJOHN CO (US) | 1987-09-30 | — | — | EP | disclosed |
| WO-1987001706-A2 | C20 THROUGH C26 AMINO STEROIDS | THE UPJOHN COMPANY (US) | 1987-03-26 | — | — | WO | disclosed |