Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD1 | Q13393 | 1/20 | 0.96 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.68 |
| ▸ | USP2 | O75604 | 3/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | BPTF | Q12830 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HTR7 | P34969 | 3/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.51 |
| ▸ | HTR3B | O95264 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL17926100 | 1.00 | PLD1 (0.96) | PLD1ALDH1A1HSD17B10USP2CYP3A4 | |
| SCHEMBL7900 | 0.98 | PLD1 (1.00) | PLD1ALDH1A1HSD17B10USP2CYP3A4 | |
| SCHEMBL893565 | 0.98 | PLD1 (1.00) | PLD1ALDH1A1HSD17B10USP2CYP3A4 | |
| SCHEMBL29400889 | 0.98 | PLD1 (1.00) | PLD1ALDH1A1HSD17B10USP2CYP3A4 | |
| Piperazine SCHEMBL27920772 | 0.96 | PLD1 (0.96) | PLD1ALDH1A1HSD17B10USP2CYP3A4 | |
| Hydrochloric Acid SCHEMBL27481639 | 0.96 | PLD1 (0.96) | PLD1ALDH1A1HSD17B10USP2CYP3A4 | |
| Bromide SCHEMBL11807389 | 0.96 | PLD1 (0.96) | PLD1ALDH1A1HSD17B10USP2CYP3A4 | |
| Hydrochloric Acid SCHEMBL4165242 | 0.96 | PLD1 (0.96) | PLD1ALDH1A1HSD17B10USP2CYP3A4 | |
| Hydrochloric Acid SCHEMBL6349557 | 0.96 | PLD1 (0.96) | PLD1ALDH1A1HSD17B10USP2CYP3A4 | |
| Hydrazine SCHEMBL9427114 | 0.94 | PLD1 (0.93) | PLD1ALDH1A1HSD17B10USP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389368-B1 | New derivatives of 6-(1-piperazinyl) 2,5-pyridine diamine N,N,N',N'-substituted, procedure for their production and intermediates, their use as medicines and pharmaceutical preparations containing them | ROUSSEL UCLAF (FR) | 1997-01-29 | — | — | EP | disclosed |