Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | MMP14 | P50281 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 8/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745996 | 0.81 | MAPT (0.57) | MAPTKMT2ATDP1MEN1MMP14 | |
| SCHEMBL11194047 | 0.81 | MAPT (0.54) | MAPTKMT2ATDP1MEN1NPSR1 | |
| SCHEMBL11194048 | 0.81 | MAPT (0.54) | MAPTKMT2ATDP1MEN1NPSR1 | |
| SCHEMBL1664726 | 0.81 | MAPT (0.71) | MAPTKMT2ATDP1MEN1MAPK1 | |
| SCHEMBL30423891 | 0.81 | MAPT (0.71) | MAPTKMT2ATDP1MEN1MAPK1 | |
| SCHEMBL8745989 | 0.80 | MAPT (0.56) | MAPTKMT2ATDP1MEN1MMP14 | |
| SCHEMBL3737780 | 0.80 | MAPT (0.56) | MAPTKMT2ATDP1MEN1MAPK1 | |
| SCHEMBL11569964 | 0.77 | MAPT (0.59) | MAPTKMT2ATDP1MEN1MAPK1 | |
| SCHEMBL4301761 | 0.76 | MAPT (0.69) | MAPTKMT2ATDP1MEN1MAPK1 | |
| SCHEMBL22261607 | 0.76 | MAPT (0.74) | MAPTKMT2ATDP1MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457182-B1 | Method having increased sensitivity, for the determination of an ion, the use of suitable substances and corresponding means therefor | BOEHRINGER MANNHEIM GMBH (DE) | 1997-02-26 | — | — | EP | disclosed |
| EP-0461392-B1 | Test carrier for the determination of ions | BOEHRINGER MANNHEIM GMBH (DE) | 1996-01-10 | — | — | EP | disclosed |
| US-5302346-A | Test carrier for the determination of ions | BOEHRINGER MANNHEIM GMBH (DE) | 1994-04-12 | — | — | US | disclosed |
| US-5215924-A | Water immiscibility; ionophore; pH indicator which undergoes color change; sensitizer/stabilizer | BOEHRINGER MANNHEIM GMBH (DE) | 1993-06-01 | — | — | US | disclosed |
| US-5211914-A | TEST CARRIER FOR THE DETERMINATION OF IONS | BOEHRINGER MANNHEIM GMBH (DE) | 1993-05-18 | — | — | US | disclosed |
| EP-0461392-A2 | Test carrier for the determination of ions | Roche Diagnostics GmbH (DE) | 1991-12-18 | — | — | EP | disclosed |
| EP-0457182-A2 | Method having increased sensitivity, for the determination of an ion, the use of suitable substances and corresponding means therefor | Roche Diagnostics GmbH (DE) | 1991-11-21 | — | — | EP | disclosed |